CAJ | 학술논문

目的评价灰阶超声造影及其量化分析技术在兔肾缺血再灌注损伤皮质显像中的诊断价值.方法建立兔肾缺血再灌注模型,15只家兔被分为术前对照I_0组,术后不同缺血时间组(I_1-I_3),用超声造影观察各组肾灌注模式并分析灌注峰值时间 (TP)、灌注峰值强度(A)、曲线上升斜率(β)、曲线下面积(AUC).结果随着缺血时间增加,超声造影显示肾皮质灌注回声逐渐变弱.灌注参数值中TP呈增加趋势,β逐渐降低,AUC先升后降,A无明显变化;与对照组比较,TP、 AUC、β、A均具有显著差异.结论超声造影及其量化分析技术可以无创地判断肾缺血再灌注损伤程度.
목적 평개회계초성조영급기양화분석기술재토신결혈재관주손상피질현상중적진단개치.방법 건립토신결혈재관주모형,15지가토피분위술전대조I_0조,술후불동결혈시간조(I_1-I_3),용초성조영관찰각조신관주모식병분석관주봉치시간 (TP)、관주봉치강도(A)、곡선상승사솔(β)、곡선하면적(AUC).결과 수착결혈시간증가,초성조영현시신피질관주회성축점변약.관주삼수치중TP정증가추세,β축점강저,AUC선승후강,A무명현변화;여대조조비교,TP、 AUC、β、A균구유현저차이.결론 초성조영급기양화분석기술가이무창지판단신결혈재관주손상정도.
Objective To evaluate the diagnostic value of gray-scale contrast-enhanced ultrasonography (CEUS) and quantitative analysis technology in the rabbit renal ischemia-reperfusion injury(IRI).Methods The rabbit model of renal IRI was estabilished.Fifteen New Zealand rabbits were divided into before surgery I_0 group,and different ischemic time (I_1-I_3) group.CEUS was used to observe the pattern of renal perfusion and perfusion peak time(TP),amplitude of peak intensity (A),curve rising slope rate (β)and area under the curve (AUC) were analysed.Results With the ischemic time increasing,CEUS showed that renal cortical perfusion echo gradually became weaker,perfusion parameter values showed increased TP,decreased β,AUC first increasing and then decreasing and A has no significant change.Compared with the normal group, TP、 AUC、β and A were all significantly different.Conclusions The CEUS and quantitative analysis technology can determine the varying degrees of renal IRI non-invasively.