CAJ | 학술논문

目的观察芪苈强心胶囊联合常规西药对慢性心力衰竭(congestive heart failure,CHF)干预作用的临床疗效.方法将61例CHF患者采用随机数字表法分为两组,对照组31例采用常规抗心衰治疗,治疗组30例在对照组治疗基础上加服芪苈强心胶囊,2周为1个疗程,共治疗2个疗程.比较两组临床疗效及治疗前后体重、尿量、6min步行距离(6MWD)、心电图、心脏超声等检查.结果 4周后,治疗组心功能改善总有效率为93.33%、对照组为74.19%,两组比较差异有统计学意义(χ~2=4.07985,P＜0.05);治疗组左室射血分数(LVEF)提高率为(16±4)%,对照组为(11±3)%,两组比较差异有统计学意义(t=5.509,P＜0.001).结论芪苈强心胶囊为主治疗CHF患者,可有效改善心功能,提高LVEF,改善临床症状,提高生活质量.
목적 관찰기력강심효낭연합상규서약대만성심력쇠갈(congestive heart failure,CHF)간예작용적림상료효.방법 장61례CHF환자채용수궤수자표법분위량조,대조조31례채용상규항심쇠치료,치료조30례재대조조치료기출상가복기력강심효낭,2주위1개료정,공치료2개료정.비교량조림상료효급치료전후체중、뇨량、6min보행거리(6MWD)、심전도、심장초성등검사.결과 4주후,치료조심공능개선총유효솔위93.33%、대조조위74.19%,량조비교차이유통계학의의(χ~2=4.07985,P＜0.05);치료조좌실사혈분수(LVEF)제고솔위(16±4)%,대조조위(11±3)%,량조비교차이유통계학의의(t=5.509,P＜0.001).결론 기력강심효낭위주치료CHF환자,가유효개선심공능,제고LVEF,개선림상증상,제고생활질량.
Objective To observe the clinical role of Qiliqiangxin capsules uniting conventional western medicine interfering with chronic heart failure(CHF).Methods 61 cases of CHF were randomly recruited into a control group(31 cases)and a treatment group(30 cases).The control group was treated with conventional anti-hean failure treatment,and the treatment group was added Qiliqiangxin capsules on the treatment of the control group.After having been treated for 2 courses (fonr weeks),such indexes as clinical efficacy,body weigbt,urine volume,6 min walking distance(6MWD),electrocardiogram,and cardiac ultrasound were measured for both groups.Results The overall efficiency of cardiac function was 93.33%for the treatment group and 74.19%for the control group.There was significant difierence between the two groups(χ~2=4.07985,P＜0.05).The enhance rate of left ventricular ejection fraction(LVEF)was(16±4)%in the treatment group as compared to(11±3)%in the control group,also showing statistical difierence between the two groups(t=5.509,P＜0.001).Conclusion Qiliqiangxin capsules combined with conventional western medicine could effectively improve the cardiac function,LVEE clinical symptoms,and quality of life in the patients with ehronic heart failure.