CAJ | 학술논문

目的探讨原发性肾上腺非霍奇金淋巴瘤的临床特征和诊治方法.方法分析我院2例原发性肾上腺淋巴瘤临床特征并复习文献.患者均为男性,年龄65岁及52岁,均以腰部隐痛为表现,通过CT检查发现双侧肾上腺占位,最终依靠穿刺活检及腹腔镜下手术组织活检确诊.结果 2例病理诊断为非霍奇金淋巴瘤,行CHOP方案化疗,1例部分缓解,定期随访.复习文献中65例完全缓解7例(10%),15例对化疗部分有效,43例死亡或失访,生存期为3 d～26个月.结论原发性肾上腺淋巴瘤大多双侧肾上腺受侵,无特征性临床症状.目前穿刺活检是确诊的首选方法.治疗包括手术、化疗或手术联合化疗、放疗,有其他器官累及的患者预后不良.
목적 탐토원발성신상선비곽기금림파류적림상특정화진치방법.방법 분석아원2례원발성신상선림파류림상특정병복습문헌.환자균위남성,년령65세급52세,균이요부은통위표현,통과CT검사발현쌍측신상선점위,최종의고천자활검급복강경하수술조직활검학진.결과 2례병리진단위비곽기금림파류,행CHOP방안화료,1례부분완해,정기수방.복습문헌중65례완전완해7례(10%),15례대화료부분유효,43례사망혹실방,생존기위3 d～26개월.결론 원발성신상선림파류대다쌍측신상선수침,무특정성림상증상.목전천자활검시학진적수선방법.치료포괄수술、화료혹수술연합화료、방료,유기타기관루급적환자예후불량.
Objective To discuss the clinical features, diagnosis and therapy of primary adrenal lymphoma (PAL) . Methods Two patients (65-year old and 52-year old respectively) who complained vague pain were analyzed. Occupying lesions in adrenal gland were discovered by computed tomography (CT) and diagnosed by needle biopsy and laparoscopic surgery. Results The two patients in our hospital were diagnosed as nonHodgkin's lymphoma. They were treated with chemotherapy and one of them was partial response. Literatures on PAL were reviewed. In the literature, 7 of the 65 patients achieved complete response, 15 partial response, 43 death or unspecified and the survival duration was 3 days to 26 months. Conclusions Most of PAL are bilateral, without specific clinical characters. Neele biopsy is the first choice to make the diagnosis. The therapeutic modalities for PAL include surgery, chemotherapy, surgery followed by chemotherapy as well as radiation therapy. The prognosis of PAL is poor if other organs are involved.