CAJ | 학술논문

目的探讨正常妇女、孕晚期妇女及妊娠糖尿病妇女的胫骨超声速率、钙代谢及骨转换的变化特点。方法 30例正常妇女、60例孕晚期妇女及31例妊娠糖尿病妇女清晨空腹抽血留尿，测定胫骨超声速率，以骨钙素为骨形成指标，尿钙及尿脱氧吡啶啉与肌酐的比值为骨吸收指标，并测定血清总钙、游离钙、总蛋白、磷、及镁。结果妊娠糖尿病妇女胫骨SOS降低明显；血清总钙、总蛋白、磷及镁均下降，尿钙/Cr与尿脱氧吡啶啉/Cr上升明显。结论妊娠期糖尿病妇女比正常孕晚期妇女骨形成减少，骨吸收增加，胫骨SOS下降。
목적 탐토정상부녀、잉만기부녀급임신당뇨병부녀적경골초성속솔、개대사급골전환적변화특점。 방법 30례정상부녀、60례잉만기부녀급31례임신당뇨병부녀청신공복추혈류뇨，측정경골초성속솔，이골개소위골형성지표，뇨개급뇨탈양필정람여기항적비치위골흡수지표，병측정혈청총개、유리개、총단백、린、급미。 결과 임신당뇨병부녀경골SOS강저명현；혈청총개、총단백、린급미균하강，뇨개/Cr여뇨탈양필정람/Cr상승명현。 결론 임신기당뇨병부녀비정상잉만기부녀골형성감소，골흡수증가，경골SOS하강。
Objective To explore the calcium metabolism in nor mal and someGestational diabetes pregnant women. Methods The women were divide d into 3 groups: 1) Gestational diabetes (n=31); 2) Normal third trimester ( n=60); 3)nonpregnant (n=30). Blood and urine samples were collected at 8 :00 a.m. following an overnight fast, in same day tibia SOS was measured by ultr asound scanner. BGP was considered valuded for bone formation markers, and the u rinary calcium and Dpy creatinine ratio valuaded for bone absorption markers. To tal calcium, free-calcium, phosphorus, magnesium and total protein were measure d. Results As compared with normal third trimester tibia SOS i n Gestational diabetes pregnant women declined . BGP, total calcium, phosphoris, magnesium, total protein decreased .The urinary calcium and Dpy creatinine rati o increased. Conclusions As compared with normal third trimest er tibia SOS in Gestational diabetes pregnant women decreased; bone formation de creased; bone absorption increased.