国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2011年
2期
188-191
,共4页
先天性心脏病%基因%PCR%比较基因组杂交
先天性心髒病%基因%PCR%比較基因組雜交
선천성심장병%기인%PCR%비교기인조잡교
Congenital heart disease%Gene%PCR%Comparative genomic hybridization
先天性心脏病的病因主要有遗传因素、环境因素和母亲因素.其遗传因素包括染色体异常、单基因缺陷和多基因缺陷.先天性心脏病遗传学检测方法近年有了飞速发展,包括染色体核型分析、荧光原位杂交、荧光定量PCR、多重连接依赖探针扩增等.
先天性心髒病的病因主要有遺傳因素、環境因素和母親因素.其遺傳因素包括染色體異常、單基因缺陷和多基因缺陷.先天性心髒病遺傳學檢測方法近年有瞭飛速髮展,包括染色體覈型分析、熒光原位雜交、熒光定量PCR、多重連接依賴探針擴增等.
선천성심장병적병인주요유유전인소、배경인소화모친인소.기유전인소포괄염색체이상、단기인결함화다기인결함.선천성심장병유전학검측방법근년유료비속발전,포괄염색체핵형분석、형광원위잡교、형광정량PCR、다중련접의뢰탐침확증등.
The etiology of congenital heart disease (CHD) incluses genetic factors, environmental factors and maternal factors. The genetic etiology of CHD includes chromosomal abnormalities, single gene defects and multiple genetic defects. The genetic testing method of CHD has made great progress in karyotype analysis,fluorescence in situ hybridization, quantitative PCR, multiplex ligation dependent probe amplification, et al.
