CAJ | 학술논문

目的研究中国人心尖肥厚型心肌病(AHCM)的临床特点及预后.方法对188例AHCM患者进行回顾性分析及随访,并对其临床表现、心血管原性病死率及心血管事件发生率进行分析.结果 188例AHCM患者中男性139例(73.9%),女性49例(26.1%),占同期肥厚型心肌病患者的16.0%,平均年龄(51.9±12.6)岁.其中,单纯型AHCM患者120例(63.8%),混合型AHCM患者68例(36.2%).171例(91.0%)患者平均随访时间(5.0±3.0)年,2例发生心血管原性死亡,心血管原性总病死率为1.2%,随访期间共28例(16.4%)患者发生心血管事件.结论中国人AHCM患病率较高,单纯型AHCM多见,预后较好.
목적 연구중국인심첨비후형심기병(AHCM)적림상특점급예후.방법 대188례AHCM환자진행회고성분석급수방,병대기림상표현、심혈관원성병사솔급심혈관사건발생솔진행분석.결과 188례AHCM환자중남성139례(73.9%),녀성49례(26.1%),점동기비후형심기병환자적16.0%,평균년령(51.9±12.6)세.기중,단순형AHCM환자120례(63.8%),혼합형AHCM환자68례(36.2%).171례(91.0%)환자평균수방시간(5.0±3.0)년,2례발생심혈관원성사망,심혈관원성총병사솔위1.2%,수방기간공28례(16.4%)환자발생심혈관사건.결론 중국인AHCM환병솔교고,단순형AHCM다견,예후교호.
Objective To analyze the clinical characteristics and prognosis of Chinese patients with apical hypertrophic cardiomyopathy (AHCM). Methods A total of 188 patients with AHCM diagnosed at Fuwai Hospital were included in this retrospective study. Clinical characteristics, mortality and cardiovascular morbidity were analyzed. A multiple logistic regression was performed to adjust for potential confounding factors. Results Males predominated with a number of 139 (73.9%) in this cohort. Patient's age ranged from 15 to 81 (51.9 ± 12. 6) years. There were 120 patients (63. 8% ) with "pure" type and 68 patients (36.2%) with "mixed" type of AHCM, 171 patients were followed up for (5.0 ± 3.0)years,cardiovascular mortality was 1.2%, 28 patients (16.4%) experienced one or more cardiovascular events. Conclusion The prevalence of AHCM is high in Chinese HCM patients, pure type AHCM is more common, and AHCM patients have a benign clinical course.