CAJ | 학술논문

棉酚(gossypol)是一种天然黄色多酚类化合物,主要存在于棉花的根、茎和种子中.最早作为一种男性节育药为人们所熟知,后又试用于治疗女性激素依赖性疾病,包括子宫内膜异位症、子宫肌瘤、功能失调性子宫出血和痛经等.进一步研究发现,棉酚具有多种生物活性,如抗炎、抗疟、抗病毒及抗氧化等,尤其是具有明显的诱导肿瘤细胞凋亡的能力.
면분(gossypol)시일충천연황색다분류화합물,주요존재우면화적근、경화충자중.최조작위일충남성절육약위인문소숙지,후우시용우치료녀성격소의뢰성질병,포괄자궁내막이위증、자궁기류、공능실조성자궁출혈화통경등.진일보연구발현,면분구유다충생물활성,여항염、항학、항병독급항양화등,우기시구유명현적유도종류세포조망적능력.
Gossypol is a kind of yellow polyphenolic compounds extracted from root, stem and seed of the cotton plant. It had received significant attention for its potential application as a male antifertility agent. Then it was used to treat female hormone-dependent diseases, for instance, endometriosis, hysteromyoma, uterine bleeding and dys-menorrheal. Current recent researches showed that gossypol has multiple biological activities, such as anti-inflammatory , antimalarial, antiviral, antioxidant activities and so on, especially the activity to induce tumor cell apoptosis.