国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2009年
4期
212-215
,共4页
人偏肺病毒%呼吸道合胞病毒%细胞因子
人偏肺病毒%呼吸道閤胞病毒%細胞因子
인편폐병독%호흡도합포병독%세포인자
Human metapneumovirus%Respiratory syneytial virus%Cytokine
人偏肺病毒与呼吸道合胞病毒是呼吸道感染的常见病原体,其感染后的发病机制尚不完全清楚,广泛接受的假说是引起机体固有免疫反应.大量研究显示两者产生不同的细胞因子效应,也提示人偏肺病毒感染的发病机制可能有别于呼吸道合胞病毒.本文就目前国内外对人偏肺病毒感染后与呼吸道合胞病毒细胞因子改变的比较研究进行综述.
人偏肺病毒與呼吸道閤胞病毒是呼吸道感染的常見病原體,其感染後的髮病機製尚不完全清楚,廣汎接受的假說是引起機體固有免疫反應.大量研究顯示兩者產生不同的細胞因子效應,也提示人偏肺病毒感染的髮病機製可能有彆于呼吸道閤胞病毒.本文就目前國內外對人偏肺病毒感染後與呼吸道閤胞病毒細胞因子改變的比較研究進行綜述.
인편폐병독여호흡도합포병독시호흡도감염적상견병원체,기감염후적발병궤제상불완전청초,엄범접수적가설시인기궤체고유면역반응.대량연구현시량자산생불동적세포인자효응,야제시인편폐병독감염적발병궤제가능유별우호흡도합포병독.본문취목전국내외대인편폐병독감염후여호흡도합포병독세포인자개변적비교연구진행종술.
Virus are the most frequent cause of viral respiratory infections for infants and young children. However,the mechanisms of the diseases that are associated with viral respiratory-tract infection are less clear. A widely accepted hypothesis attributes the pathogenesis of viral respiratory infections to the induction of innate inflammatory responses. Infection with human metapneumovirus was second only to respiratory syncytial virus in frequency. In this review, human metapneumovirus and respiratory syncytial virus elicit different cytokine responses and the pathogeneses of these agents should be studied individually.