中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2010年
8期
707-709
,共3页
ADHD%反向眼跳%反应抑制%工作记忆
ADHD%反嚮眼跳%反應抑製%工作記憶
ADHD%반향안도%반응억제%공작기억
Attention deficit hyperactivity disorder%Antisaccade%Response inhibition%Working memory
目的 使用眼跳任务深入探究不同亚型注意缺陷多动障碍(Attention deficit hyperactivity disorder,ADHD)儿童的抑制缺陷和工作记忆损伤.方法 采用随机整群抽样方法 选取1500名小学生,使用DSM-Ⅳ诊断标准、Conners 儿童行为量表(父母问卷和教师问卷)进行筛查.48名被试,年龄10～13岁,注意缺陷型(Ⅰ型)11人,混合型(C型)19人,对照组18人.全体进行了正向眼跳、反向眼跳和加载工作记忆的反向眼跳.结果 (1)反向眼跳时各组错误率比正向眼跳时显著提高,对照组成绩[(37.97±13.14)%]显著好于ADHD儿童(P＜0.01),且Ⅰ型的错误率低于C型[(70.90±15.78)%,(84.04±12.84)%,P＜0.05].(2)错误率的加载与组别的交互作用无统计学意义(P＞0.1),矫正率的加载与组别的交互作用具有统计学意义(P＜0.05),其中对照组加载效应无统计学意义(P＞0.1),Ⅰ型和C型的加载效应具有统计学意义(P＜0.05).结论 研究提示两亚型ADHD儿童存在抑制损伤和工作记忆损伤,Ⅰ型的抑制功能好于C型.
目的 使用眼跳任務深入探究不同亞型註意缺陷多動障礙(Attention deficit hyperactivity disorder,ADHD)兒童的抑製缺陷和工作記憶損傷.方法 採用隨機整群抽樣方法 選取1500名小學生,使用DSM-Ⅳ診斷標準、Conners 兒童行為量錶(父母問捲和教師問捲)進行篩查.48名被試,年齡10～13歲,註意缺陷型(Ⅰ型)11人,混閤型(C型)19人,對照組18人.全體進行瞭正嚮眼跳、反嚮眼跳和加載工作記憶的反嚮眼跳.結果 (1)反嚮眼跳時各組錯誤率比正嚮眼跳時顯著提高,對照組成績[(37.97±13.14)%]顯著好于ADHD兒童(P＜0.01),且Ⅰ型的錯誤率低于C型[(70.90±15.78)%,(84.04±12.84)%,P＜0.05].(2)錯誤率的加載與組彆的交互作用無統計學意義(P＞0.1),矯正率的加載與組彆的交互作用具有統計學意義(P＜0.05),其中對照組加載效應無統計學意義(P＞0.1),Ⅰ型和C型的加載效應具有統計學意義(P＜0.05).結論 研究提示兩亞型ADHD兒童存在抑製損傷和工作記憶損傷,Ⅰ型的抑製功能好于C型.
목적 사용안도임무심입탐구불동아형주의결함다동장애(Attention deficit hyperactivity disorder,ADHD)인동적억제결함화공작기억손상.방법 채용수궤정군추양방법 선취1500명소학생,사용DSM-Ⅳ진단표준、Conners 인동행위량표(부모문권화교사문권)진행사사.48명피시,년령10～13세,주의결함형(Ⅰ형)11인,혼합형(C형)19인,대조조18인.전체진행료정향안도、반향안도화가재공작기억적반향안도.결과 (1)반향안도시각조착오솔비정향안도시현저제고,대조조성적[(37.97±13.14)%]현저호우ADHD인동(P＜0.01),차Ⅰ형적착오솔저우C형[(70.90±15.78)%,(84.04±12.84)%,P＜0.05].(2)착오솔적가재여조별적교호작용무통계학의의(P＞0.1),교정솔적가재여조별적교호작용구유통계학의의(P＜0.05),기중대조조가재효응무통계학의의(P＞0.1),Ⅰ형화C형적가재효응구유통계학의의(P＜0.05).결론 연구제시량아형ADHD인동존재억제손상화공작기억손상,Ⅰ형적억제공능호우C형.
Objective To analyze inhibitions and working memory impairments in children with different subtypes of attention deficit hyperactivity disorder (ADHD) with saccade tasks. Methods Participants,aged 10～ 13 years with ADHD-combined ( n= 19) ,ADHD-inattentive ( n= 11 ) and control subjects ( n= 18) ,were selected according to DSM-Ⅳ diagnosis,Conners teacher rating scale and parent symptom questionnaire from 1500pupils from 2 primary schools in Jinhua city by stratified cluster sampling method. Participants performed 3 different saccade tasks: 1 prosaccade and 2 antisaccades executed in a single-task and a dual-task situation. One of the antisaccade tasks was performed under the verbal secondary task condition to investigate verbal working memory.Saccades were registered by Eyelink Ⅱ Tracker. Errors and correct rate were analyzed. One-way ANOVA and repeated measures ANOVA were used to analyze the data. Results (1) Each group showed more response suppression errors on antisaccade task without load than on prosaccade task, ADHD-combined and ADHD-inattentive exhibited more errors than non-ADHD (P＜0.01) ,and errors was lower in ADHD-inattentive than in ADHD-combined ( ( 70.90 ± 15.78 ) % vs ( 84.04 ± 12.84 ) %, P ＜ 0.05 ). (2) The interactions between group and load were not significant in error rate on antisaccade tasks (P ＞ 0.05 ), but in correct rate (P ＜ 0. 05 ). The two subtypes of ADHD were affected more than non-ADHD, their correct rates tended to decrease under verbal working memory load. Conclusion An integrative view of deficits in inhibition and verbal working memory in two subtypes of ADHD is proposed, and ADHD-inattentive has a better response suppression than ADHD-combined.
