CAJ | 학술논문

　　帕金森病是中老年人常见的神经变性疾病，以黑质致密部多巴胺能神经元进行性缺失、纹状体多巴胺水平降低为主要特点。中枢神经系统炎症和全身炎症都会导致多巴胺能神经元变性和死亡；抑制中枢神经炎症，靶向调节全身炎症、减轻外周损伤对大脑的影响，有助于缓解和阻止病情的发展，给帕金森病的预防和治疗提供新思路。
　　파금삼병시중노년인상견적신경변성질병，이흑질치밀부다파알능신경원진행성결실、문상체다파알수평강저위주요특점。중추신경계통염증화전신염증도회도치다파알능신경원변성화사망；억제중추신경염증，파향조절전신염증、감경외주손상대대뇌적영향，유조우완해화조지병정적발전，급파금삼병적예방화치료제공신사로。
Parkinson's disease is a common progressive neurodegenerative disorder among old people, characterized by progressive loss of dopamine-producing neurons in the substantia nigra pars compacta and accordingly low level of dopamine in the nigrostriatal path-way. Neuroinflammation and even systemic inflammation have been suggested to be involved in the demise of dopaminergic neurons. An-ti-inflammatory treatment could protect brain from inflammatory injury and prevent the progressive course of Parkinson's disease, which suggests a potential new strategy for Parkinson's disease treatment.