CAJ | 학술논문

目的：探讨国产阿卡波糖片(卡博平)治疗2型糖尿病的疗效及安全性。方法：将2012年8月至2013年8月开平市第二人民医院收治的40例2型糖尿病患者随机分为观察组(国产阿卡波糖卡博平,20例)和对照组(进口阿卡波糖卡拜唐苹,20例),治疗8周后,观察两组空腹及餐后2 h血糖、糖化血红蛋白、TG、TC、HDL C、等指标。结果：治疗8周后,两组空腹及餐后血糖、HbA1c较治疗前均明显下降,治疗前后比较,差异有统计学意义(P<0.05),但两组比较,差异无统计学意义(P>0.05)。与治疗前相比,两组治疗8周后TG、TC、HDL C等比较,差异均无统计学意义( P>0.05)。两组不良反应比较,差异无统计学意义( P>0.05)。结论：国产阿卡波糖片卡博平是一种有效的口服抗高血糖药物,具有与拜唐苹相近的有效性和安全性。
목적：탐토국산아잡파당편(잡박평)치료2형당뇨병적료효급안전성。방법：장2012년8월지2013년8월개평시제이인민의원수치적40례2형당뇨병환자수궤분위관찰조(국산아잡파당잡박평,20례)화대조조(진구아잡파당잡배당평,20례),치료8주후,관찰량조공복급찬후2 h혈당、당화혈홍단백、TG、TC、HDL C、등지표。결과：치료8주후,량조공복급찬후혈당、HbA1c교치료전균명현하강,치료전후비교,차이유통계학의의(P<0.05),단량조비교,차이무통계학의의(P>0.05)。여치료전상비,량조치료8주후TG、TC、HDL C등비교,차이균무통계학의의( P>0.05)。량조불량반응비교,차이무통계학의의( P>0.05)。결론：국산아잡파당편잡박평시일충유효적구복항고혈당약물,구유여배당평상근적유효성화안전성。
Objective:To determine the efficacy and safety of acarbose tablets ( KabopingTM ) in type 2 diabetes mellitus. Methods: Between August 2012 and August 2013, we recruited 40 patients with type 2 diabetes mellitus from Kaiping Second People’ s Hospital who were randomly allocated to be treated with an 8 week course of acarbose tablets ( KabopingTM for control group ( n=20) and GlucobayTM for treatment group ( n=20) . This entailed assessment of fasting and 2 h postprandial blood glucose, glycosylated hemoglobin, total glycerin (TG), total cholesterol (TC) and high density lipoprotein cholesterol (HDL C) before and after the treatment. Results:Treatment with acarbose tables in both groups yielded similarly marked reduction in the levels of fasting and 2h postprandial blood glucose and glycosylated hemoglobin (all P<0.05), but not TG, TC and HDL C ( all P>0. 05) . The between group differences in adverse reactions were not statistically significant ( P>0. 05) . Conclusion: Compared with GlucobayTM tablets, KabopingTM tablets are associated with similar efficacy and safety for the treatment of type 2 diabetes mellitus.