CAJ | 학술논문

　　目的分析血清同型半胱氨酸（Hcy）水平与非心力衰竭初发急性 ST 段抬高型心肌梗死患者冠状动脉病变程度有无相关性及其临床意义。方法选取非心力衰竭急性心肌梗死患者65例，对照组20名为我院体检中心健康体检者。入院次日晨空腹测定各组 Hcy 水平，将冠状动脉病变程度与 Hcy 水平进行相关性分析，并对不同梗死部位的 Hcy 水平进行比较。所得数据采用 SPSS 19.0统计软件进行分析。计量资料采用（均数±标准差）表示，应用 t 检验进行分析。Hcy 与冠状动脉评分之间采用 Pearson 相关分析。P ＜0.05为显著性差异。结果急性心肌梗死组 Hcy 水平显著高于对照组（P ＜0.001）。血浆 Hcy 水平与冠状动脉病变评分呈正相关关系，相关系数为 r=0.695。结论在排除心力衰竭因素后，Hcy 水平越高，急性心肌梗死患者冠状动脉病变程度越重。Hcy 测定有助于急性心肌梗死患者的危险分层及预后判断。
　　목적분석혈청동형반광안산（Hcy）수평여비심력쇠갈초발급성 ST 단태고형심기경사환자관상동맥병변정도유무상관성급기림상의의。방법선취비심력쇠갈급성심기경사환자65례，대조조20명위아원체검중심건강체검자。입원차일신공복측정각조 Hcy 수평，장관상동맥병변정도여 Hcy 수평진행상관성분석，병대불동경사부위적 Hcy 수평진행비교。소득수거채용 SPSS 19.0통계연건진행분석。계량자료채용（균수±표준차）표시，응용 t 검험진행분석。Hcy 여관상동맥평분지간채용 Pearson 상관분석。P ＜0.05위현저성차이。결과급성심기경사조 Hcy 수평현저고우대조조（P ＜0.001）。혈장 Hcy 수평여관상동맥병변평분정정상관관계，상관계수위 r=0.695。결론재배제심력쇠갈인소후，Hcy 수평월고，급성심기경사환자관상동맥병변정도월중。Hcy 측정유조우급성심기경사환자적위험분층급예후판단。
Objective To analyze the serum homocysteine (Hcy) level and non heart failure in primary acute myocardial infarction patients with ST segment elevation extent of coronary artery lesions have no correlation and its clinical significance. Methods 65 patients with non heart failure, acute myocardial infarction, 20 patients in the control group for the health examination center. The fasting levels were measured in each Hcy, the severity of coronary artery lesion and the level of Hcy correlation analysis, and compares the different infarct Hcy level. The obtained data were analyzed using SPSS 19.0 statistical software. Measurement data using (mean ± standard deviation) said, using t test analysis. Using Pearson correlation analysis between Hcy and coronary artery score. P < 0.05 was significant difference. Results Acute myocardial infarction group, Hcy level was significantly higher than that of the control group (P < 0.001). Correlation between plasma Hcy level and coronary lesion score was positively, the correlation coefficient is r =0.695. Conclusion In the exclusion of failure factors, the higher the Hcy level, the more severe lesions of coronary artery in patients with acute myocardial infarction degree. Hcy determination of risk stratification and prognosis is helpful for patients with acute myocardial infarction.