CAJ | 학술논문

目的：观察对于急性ST段抬高型心肌梗死(STEMI)早期再灌注治疗后外周血白细胞（WBC）计数与心脏事件的变化及两者的关系。方法将151例发病3 h内开始再灌注治疗的STEMI患者分成急诊经皮冠状动脉介入（PCI）治疗组52例（PCI组）和阿替普酶溶栓组99例（溶栓组），记录并比较2组发病4 d内WBC与心脏事件变化。结果 PCI组治疗后2 d、4 d的WBC及心脏事件均低于溶栓组，差异有统计学意义（P<0.05），治疗后2 d的WBC与心脏事件呈正相关（r=0.226，P<0.05）。结论急诊PCI术后的WBC与心脏事件明显降低，STEMI后WBC升高程度与近期心脏事件相关。
목적：관찰대우급성ST단태고형심기경사(STEMI)조기재관주치료후외주혈백세포（WBC）계수여심장사건적변화급량자적관계。방법장151례발병3 h내개시재관주치료적STEMI환자분성급진경피관상동맥개입（PCI）치료조52례（PCI조）화아체보매용전조99례（용전조），기록병비교2조발병4 d내WBC여심장사건변화。결과 PCI조치료후2 d、4 d적WBC급심장사건균저우용전조，차이유통계학의의（P<0.05），치료후2 d적WBC여심장사건정정상관（r=0.226，P<0.05）。결론급진PCI술후적WBC여심장사건명현강저，STEMI후WBC승고정도여근기심장사건상관。
Objective To study the relationship between blood cell count and cardiac events in acute ST elevation myocardial infarction patients treated with reperfusion in the early stage. Methods In this study, we assigned 151 patients to whom reperfusion therapy had been delivered within 3 hours of STEMI symptom into two groups:primary percutaneous cor-onary intervention group and thrombolysis therapy group. Differences of cardiac events and white blood cell count in these two groups were analyzed in the first 4 days. Results In the second day and the forth day, cardiac events rate and white blood cell count were significantly lower in the primary percutaneous coronary intervention group than those in the thromboly-sis therapy group (P<0.05). In the second day, white blood cell count has a positive correlation with cardiac events rate (r=0.226, P<0.05). Conclusion Primary percutaneous coronary intervention decreased blood cell count and cardiac events rate. In patients with acute myocardial infarction, increasing white blood cell was related to cardiac events in the near future.