临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2014年
9期
721-723
,共3页
炎症性肠病%自主神经功能%对比
炎癥性腸病%自主神經功能%對比
염증성장병%자주신경공능%대비
Inflammatory bowel disease%Autonomic nervous%Contrast
目的：探讨炎症性肠病（IBD）患者的自主神经功能改变状况。方法分析2012年1月至2014年2月在消化内科接受住院或是门诊治疗的 IBD 患者[溃疡性结肠炎（UC）和克罗恩病（CD）]的临床资料，并选取正常体检者作为对照组。两组受试者均行迷走副交感神经和交感肾上腺能神经功能的检查。结果共纳入研究对象105例，其中 IBD 患者70例（UC 患者38例，CD 32例），对照组35例。IBD 患者的卧立位心率变化值均显著低于对照组，差异具有统计学意义（ t =4.025，P <0.001）；两组受试者的瓦氏指数相比差异无统计学差异（ t =0.400，P =0.690）。IBD 组患者的卧立位血压差值显著高于对照组（ t =2.845，P <0.001）；IBD 组患者的握力实验血压差值均显著低于对照组，差异具有统计学意义（ t =8.273，P <0.001）。结论 IBD 患者相对于正常对照组，其交感肾上腺素能神经系统功能明显增强，而迷走副交感神经功能相对有所减弱。
目的：探討炎癥性腸病（IBD）患者的自主神經功能改變狀況。方法分析2012年1月至2014年2月在消化內科接受住院或是門診治療的 IBD 患者[潰瘍性結腸炎（UC）和剋囉恩病（CD）]的臨床資料，併選取正常體檢者作為對照組。兩組受試者均行迷走副交感神經和交感腎上腺能神經功能的檢查。結果共納入研究對象105例，其中 IBD 患者70例（UC 患者38例，CD 32例），對照組35例。IBD 患者的臥立位心率變化值均顯著低于對照組，差異具有統計學意義（ t =4.025，P <0.001）；兩組受試者的瓦氏指數相比差異無統計學差異（ t =0.400，P =0.690）。IBD 組患者的臥立位血壓差值顯著高于對照組（ t =2.845，P <0.001）；IBD 組患者的握力實驗血壓差值均顯著低于對照組，差異具有統計學意義（ t =8.273，P <0.001）。結論 IBD 患者相對于正常對照組，其交感腎上腺素能神經繫統功能明顯增彊，而迷走副交感神經功能相對有所減弱。
목적：탐토염증성장병（IBD）환자적자주신경공능개변상황。방법분석2012년1월지2014년2월재소화내과접수주원혹시문진치료적 IBD 환자[궤양성결장염（UC）화극라은병（CD）]적림상자료，병선취정상체검자작위대조조。량조수시자균행미주부교감신경화교감신상선능신경공능적검사。결과공납입연구대상105례，기중 IBD 환자70례（UC 환자38례，CD 32례），대조조35례。IBD 환자적와립위심솔변화치균현저저우대조조，차이구유통계학의의（ t =4.025，P <0.001）；량조수시자적와씨지수상비차이무통계학차이（ t =0.400，P =0.690）。IBD 조환자적와립위혈압차치현저고우대조조（ t =2.845，P <0.001）；IBD 조환자적악력실험혈압차치균현저저우대조조，차이구유통계학의의（ t =8.273，P <0.001）。결론 IBD 환자상대우정상대조조，기교감신상선소능신경계통공능명현증강，이미주부교감신경공능상대유소감약。
Objective To investigate the changes of autonomic nervous function in patients with inflammation bowel diseases(IBD). Methods From 2012 January to 2014 February,clinical data was analyzed for inpatient or outpatient treatment of IBD patients(UC and CD)in our hospital department of internal medicine digestion. Health examinations people were selected as the normal controls. Two groups of subjects un-derwent vagal parasympathetic and sympathetic adrenergic nerve function tests. Results 70 cases of IBD patients were selected into this study. The control group included 35 cases. IBD group with orthostatic heart rate values were significantly lower than those in the control group( t = 4. 025,P < 0. 01). Warburg index of two groups showed no significant difference( t = 0. 400,P = 0. 690). IBD patients with orthostatic blood pressure values were higher than in the control group( t = 2. 845,P < 0. 001). While difference grip experimental blood pressure in IBD patients were significantly lower than the control group( t = 8. 273,P < 0. 001). Conclusion In patients with IBD compared with normal control group, the sympathetic adrenergic nerve system function was strengthened,and the vagal parasympathetic nerve function relatively weakened.
