CAJ | 학술논문

　　目的探讨感统训练对轻度认知功能障碍（MCI）老年人氢质子磁共振波谱（1H－MRS）的影响。方法将入选的16例60～70岁的MCI老年人，在课题组人员指导下进行感统训练半年，每周5d，训练前后分别进行MRI扫描，比较其N－乙酰天门冬氨酸（NAA）/肌酸（Cr），胆碱（Cho）/Cr，肌醇（mI）/Cr的差别。结果训练前后海马区NAA/Cr和mI/Cr水平有显著性差异，训练后NAA/Cr水平较训练前升高，mI/Cr水平较训练前明显降低（P＜0．05）；训练前后Cho/Cr水平差异无显著性（P＞0．05）。结论感统训练能改变脑内海马区代谢产物的浓度，使NAA/Cr，mI/Cr改变。
　　목적탐토감통훈련대경도인지공능장애（MCI）노년인경질자자공진파보（1H－MRS）적영향。방법장입선적16례60～70세적MCI노년인，재과제조인원지도하진행감통훈련반년，매주5d，훈련전후분별진행MRI소묘，비교기N－을선천문동안산（NAA）/기산（Cr），담감（Cho）/Cr，기순（mI）/Cr적차별。결과훈련전후해마구NAA/Cr화mI/Cr수평유현저성차이，훈련후NAA/Cr수평교훈련전승고，mI/Cr수평교훈련전명현강저（P＜0．05）；훈련전후Cho/Cr수평차이무현저성（P＞0．05）。결론감통훈련능개변뇌내해마구대사산물적농도，사NAA/Cr，mI/Cr개변。
Objective To investigate the effcet of sensory integration training on H magnetic resonance spectroscopy (H-MRS) in patients with mild cognitive impairment .Methods Sixteen elderly aged 60~70 years old with MCI received sensory integration training for five days a week for six months guided by members of research group .MRI scanning was performed before and after the training in order to compare the differences of the ratios between NAA/Cr,Cho/Cr and mI/Cr.Results There were significant difference between the levels of NAA/Cr and mI/Cr in hippocampus before and after the training .NAA/Cr level after the training was higher than before ,thus mI/Cr level af-ter the training was lower than before with statistical significance (P<0.05).There were no statistical significance of Cho/Cr level before and after the training(P>0.05).Conclusion Sensory integration training can change the concentration of the metabolites in hippocampus and convert the ratios of NAA/Cr and mI/Cr.