CAJ | 학술논문

　　目的研究部分睡眠剥夺对健康男性血清皮质醇及认知功能的影响。方法采用交叉设计的自身对照性试验研究，14例健康男性先进入上半夜睡眠剥夺，经过7d睡眠洗脱期，进入下半夜睡眠剥夺，每个睡眠剥夺包括7d。每个睡眠剥夺晨起7：00时抽取空腹血测定血清皮质醇，每日12：00时行快速敲击键盘任务，单词记忆和单词识别测试。结果睡眠剥夺均导致皮质醇的下降，剥夺下半夜睡眠比上半夜更明显，恢复睡眠后，皮质醇恢复到未剥夺前的状态，睡眠剥夺均导致记忆、操作能力和注意力的下降，剥夺上半夜睡眠表现更为明显。结论睡眠剥夺对机体的认知功能和血清皮质醇的分泌存在明显影响。
　　목적연구부분수면박탈대건강남성혈청피질순급인지공능적영향。방법채용교차설계적자신대조성시험연구，14례건강남성선진입상반야수면박탈，경과7d수면세탈기，진입하반야수면박탈，매개수면박탈포괄7d。매개수면박탈신기7：00시추취공복혈측정혈청피질순，매일12：00시행쾌속고격건반임무，단사기억화단사식별측시。결과수면박탈균도치피질순적하강，박탈하반야수면비상반야경명현，회복수면후，피질순회복도미박탈전적상태，수면박탈균도치기억、조작능력화주의력적하강，박탈상반야수면표현경위명현。결론수면박탈대궤체적인지공능화혈청피질순적분비존재명현영향。
Objective To investigate the effects of short-term sleep deprivation(SD)at different time during night on serum cortisol level and cognition function of healthy men .Methods Crossover design their own controlled trial was used,14 healthy men were first to enter the late-sleep deprivation,after a washout period of seven days of sleep into the midnight sleep deprivation,each sleep deprivation include 7 days.Early morning 7:00 fasting blood serum cortisol was collected after each sleep deprivation.The daily 12:00 line quick keystrokes task,word memory and word recognition test were taken.Results The cortisol levels lowered after 2 types of SD,and more obviously of deprivation the midnight sleep than the late-sleep,Cortisol recover to the state of not deprive after sleep recovery .Sleep deprivation lead to a de-cline in memory,operating capacity and attention,deprive midnight sleep became more evident .Conclusion Sleep dep-rivation significantly affect the body cognitive function and serum cortisol secretion .