CAJ | 학술논문

目的：探讨亚低温疗法对重型、极重型流行性乙型脑炎的疗效。方法收集2008年1月至2013年1月某儿童医院PICU接受治疗的流行性乙型脑炎患者60例病例资料，其中亚低温治疗组27例，常规治疗组33例。比较两组患者治疗后格拉斯哥昏迷评分（GCS）、生命体征等临床指标以及治疗效果。结果亚低温组GCS 评分较对照组高，体温和心率较对照组低，且差异均有统计学意义（P＜0．01）；亚低温组，治愈21例（77．8％），有效4例（14．8％），无效（7．4％）；对照组，治愈15例（45．4％），有效12例（36．4％），无效6例（18．2％），两组之间差异有统计学意义（P＜0．05）；但两组血压和血氧饱和度（SpO2）比较差异无统计学意义（P＞0．05）。结论在常规药物治疗的基础上，亚低温治疗有助于保护患儿的脑功能，改善其预后，提高生存率。
목적：탐토아저온요법대중형、겁중형류행성을형뇌염적료효。방법수집2008년1월지2013년1월모인동의원PICU접수치료적류행성을형뇌염환자60례병례자료，기중아저온치료조27례，상규치료조33례。비교량조환자치료후격랍사가혼미평분（GCS）、생명체정등림상지표이급치료효과。결과아저온조GCS 평분교대조조고，체온화심솔교대조조저，차차이균유통계학의의（P＜0．01）；아저온조，치유21례（77．8％），유효4례（14．8％），무효（7．4％）；대조조，치유15례（45．4％），유효12례（36．4％），무효6례（18．2％），량조지간차이유통계학의의（P＜0．05）；단량조혈압화혈양포화도（SpO2）비교차이무통계학의의（P＞0．05）。결론재상규약물치료적기출상，아저온치료유조우보호환인적뇌공능，개선기예후，제고생존솔。
Objective To explore the curative effect of hypothermia therapy for severe,very severe epidemic encephalitis B.Meth-ods We collected data of 60 cases of epidemic encephalitis B from January 2008 to January 2013 who accepted the treatment in PICU of a children's hospital.Twenty-seven cases consisted of the mild hypothermia treatment group,while 33 cases for conventional treatment group. Glasgow Coma Scale (GCS),vital signs and other clinical indicators and treatment effect were compared between the two groups.Results GCS score of hypothermia group was higher than that of the control group,while body temperature and heart rate was lower,and the differences were all statistically significant (P<0.01).In mild hypothermia group,21 cases were cured (77.8%),4 cases effective(14.8%),and 2 ca-ses invalid(7.4%);in control group,15 cases were cured (45.4%),12 cases effective(36.4%),and 6 cases invalid(18.2%).The difference was also statistically significant between the two groups (P<0.05).However,no significant difference was found both in blood pressure and blood oxygen saturation (SpO2 )between the two groups(P>0.05 ).Conclusion On the basis of routine therapy,mild hypothermia treat-ment helps to protect children's brain function,improve the prognosis,and improve the survival rate.