CAJ | 학술논문

膳食纤维是一种特殊营养素，其本质是碳水化合物中不能被人体消化酶所分解多糖类物质。根据其水溶性可将膳食纤维分为可溶性膳食纤维和不可溶性膳食纤维；可溶性膳食纤维是既能溶解于水，又能吸水膨胀，并能被大肠中微生物降解纤维。可溶性膳食纤维可降血脂、降胆固醇及预防心血管疾病；降血糖，减少糖尿病发生；同时，其还能诱导肿瘤细胞凋亡，预防肿瘤发生和进展。该文从流行病学、临床试验及动物和细胞实验等方面综述可溶性膳食纤维生理功能及分子机制最新进展，并对未来研究进行展望。
선식섬유시일충특수영양소，기본질시탄수화합물중불능피인체소화매소분해다당류물질。근거기수용성가장선식섬유분위가용성선식섬유화불가용성선식섬유；가용성선식섬유시기능용해우수，우능흡수팽창，병능피대장중미생물강해섬유。가용성선식섬유가강혈지、강담고순급예방심혈관질병；강혈당，감소당뇨병발생；동시，기환능유도종류세포조망，예방종류발생화진전。해문종류행병학、림상시험급동물화세포실험등방면종술가용성선식섬유생리공능급분자궤제최신진전，병대미래연구진행전망。
Dietary fiber is a special nutrient. It is carbohydrates which can not be digested by enzymes to break down the polysaccharides. According to its water-soluble characteristics,dietary fiber can be divided into soluble dietary fiber and insoluble dietary fiber. Soluble dietary fiber can dissolve in water and swelling,and it also can degradated microbiaum in the large intestine. Soluble dietary fiber has effects of reducing blood lipids,lowering cholesterol and preventing cardiovascular diseases, reducing blood sugar and lowering diabetes. At the same time,it can induce apoptosis of tumor cells and preventing tumor occurrence and progression. In this paper,we summarized the progress in physiological function of soluble dietary fiber from epidemics studies,clinical trials,as well as animal and cell experiments,and the molecular mechanism of soluble dietary fiber in preventing diseases. We also make prospects for future research in the fields.