中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
43期
7012-7017
,共6页
张祥%王增亮%陈丹莉%吴淦春%徐丹书%汪永新
張祥%王增亮%陳丹莉%吳淦春%徐丹書%汪永新
장상%왕증량%진단리%오감춘%서단서%왕영신
生物材料%材料相容性%钛网%开放性%粉碎性颅骨骨折%Ⅰ期修补%并发症%住院费用
生物材料%材料相容性%鈦網%開放性%粉碎性顱骨骨摺%Ⅰ期脩補%併髮癥%住院費用
생물재료%재료상용성%태망%개방성%분쇄성로골골절%Ⅰ기수보%병발증%주원비용
背景:目前国内外学者普遍认为钛网理化性优良,易塑形,易裁剪,耐腐蚀性及耐磨损性好,无磁性,对CT或MRI结果影响较小,而且具有良好的抗压性,组织相容性好,是较理想的颅骨修补材料。<br> 目的:探讨钛网Ⅰ期修补在开放性、粉碎性颅骨骨折中应用的可行性。<br> 方法:回顾性分析62例开放性、粉碎性颅骨骨折患者的临床资料,男49例,女13例,年龄7-69岁,其中30例Ⅰ期仅行清创,术后6-12个月再行钛网颅骨修补,作为对照组;另32例清创的同时Ⅰ期行钛网颅骨修补,作为观察组。随访1至2年,观察两组切口愈合、并发症及住院费用。<br> 结果与结论:随访1至2年,62例患者均未发生切口感染与颅内感染;对照组术后颅内血肿、癫痫发生率及其他并发症发生率均高于观察组(P <0.05),住院费用高于观察组(P <0.05)。结果表明在掌握严格适应证的开放性、粉碎性颅骨骨折中,钛网Ⅰ期修补是完全可行的,能明显减少并发症的发生,降低住院费用。
揹景:目前國內外學者普遍認為鈦網理化性優良,易塑形,易裁剪,耐腐蝕性及耐磨損性好,無磁性,對CT或MRI結果影響較小,而且具有良好的抗壓性,組織相容性好,是較理想的顱骨脩補材料。<br> 目的:探討鈦網Ⅰ期脩補在開放性、粉碎性顱骨骨摺中應用的可行性。<br> 方法:迴顧性分析62例開放性、粉碎性顱骨骨摺患者的臨床資料,男49例,女13例,年齡7-69歲,其中30例Ⅰ期僅行清創,術後6-12箇月再行鈦網顱骨脩補,作為對照組;另32例清創的同時Ⅰ期行鈦網顱骨脩補,作為觀察組。隨訪1至2年,觀察兩組切口愈閤、併髮癥及住院費用。<br> 結果與結論:隨訪1至2年,62例患者均未髮生切口感染與顱內感染;對照組術後顱內血腫、癲癇髮生率及其他併髮癥髮生率均高于觀察組(P <0.05),住院費用高于觀察組(P <0.05)。結果錶明在掌握嚴格適應證的開放性、粉碎性顱骨骨摺中,鈦網Ⅰ期脩補是完全可行的,能明顯減少併髮癥的髮生,降低住院費用。
배경:목전국내외학자보편인위태망이화성우량,역소형,역재전,내부식성급내마손성호,무자성,대CT혹MRI결과영향교소,이차구유량호적항압성,조직상용성호,시교이상적로골수보재료。<br> 목적:탐토태망Ⅰ기수보재개방성、분쇄성로골골절중응용적가행성。<br> 방법:회고성분석62례개방성、분쇄성로골골절환자적림상자료,남49례,녀13례,년령7-69세,기중30례Ⅰ기부행청창,술후6-12개월재행태망로골수보,작위대조조;령32례청창적동시Ⅰ기행태망로골수보,작위관찰조。수방1지2년,관찰량조절구유합、병발증급주원비용。<br> 결과여결론:수방1지2년,62례환자균미발생절구감염여로내감염;대조조술후로내혈종、전간발생솔급기타병발증발생솔균고우관찰조(P <0.05),주원비용고우관찰조(P <0.05)。결과표명재장악엄격괄응증적개방성、분쇄성로골골절중,태망Ⅰ기수보시완전가행적,능명현감소병발증적발생,강저주원비용。
BACKGROUND:At present, scholars general y believe that the physical and chemical properties of titanium mesh are fine as easy plastic, easy cutting, good corrosion resistance and wear resistance, non-magnetic, less effect on CT or MRI results, good histocompatibility and resistance to stress. The titanium mesh is regarded as an ideal material for cranioplasty. <br> OBJECTIVE:To explore the clinical feasibility of primary reconstruction of comminuted and open skul fracture with titanium mesh. <br> METHODS:Sixty-two cases of comminuted and open skul fracture were analyzed retrospectively, including 49 males and 13 females, aged 7-69 years. Among these 62 patients, 30 patients underwent debridement and then after 6-12 months, they received titanium mesh reconstruction, serving as control group. Another 32 cases underwent debridement and titanium mesh reconstruction in the same time as observation group. Al the cases were fol owed-up for 1-2 years to observe wound healing, complications and hospitalization cost. <br> RESULTS AND CONCLUSION:During the fol ow-up, no wound infection and intracranial infection occurred in the two groups. The incidence of intracranial hematoma, epilepsy, and other complications was higher in the control group than the observation group (P<0.05), and the hospitalization cost was also higher in the control group than the observation group (P<0.05). These findings indicate that primary reconstruction with titanium mesh is feasible in the treatment of comminuted and open skul fracture and can significantly reduce the incidence of complications and hospitalization costs.