中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
43期
6922-6928
,共7页
吴强%莫世赞%包拥政%胡孔和%何小龙%朱文刚%席新华%钟学仁%徐锦明
吳彊%莫世讚%包擁政%鬍孔和%何小龍%硃文剛%席新華%鐘學仁%徐錦明
오강%막세찬%포옹정%호공화%하소룡%주문강%석신화%종학인%서금명
生物材料%骨生物材料%骨质疏松椎体压缩性骨折%椎体成形%CT三维重建%骨水泥%弥散特征
生物材料%骨生物材料%骨質疏鬆椎體壓縮性骨摺%椎體成形%CT三維重建%骨水泥%瀰散特徵
생물재료%골생물재료%골질소송추체압축성골절%추체성형%CT삼유중건%골수니%미산특정
背景:椎体成形及椎体后凸成形可有效治疗骨质疏松性椎体压缩性骨折,但两种手术方式在骨水泥的分布与弥散上有差异。<br> 目的:分析骨水泥行椎体成形或后凸成形治疗骨质疏松椎体压缩性骨折后在椎体内弥散的影响因素。<br> 方法:纳入41例骨质疏松椎体压缩性骨折患者,其中22例进行高黏度骨水泥椎体成形治疗(A组),5例进行高黏度骨水泥椎体后凸成形治疗(B组),14例进行低黏度骨水泥椎体成形治疗(C组)。再根据骨水泥注射量、骨折至手术时间、术前椎体压缩程度将A、C组进行亚组分析。通过CT三维成像和容积再现分析骨水泥在椎体内的分布及弥散。<br> 结果与结论:3组术后骨水泥在椎体内的相对弥散面积及相对弥散体积无明显区别,均能较好地弥散到上下椎板并越过椎体中线。3组骨水泥弥散系数差异无显著性意义。在一定范围内,骨水泥注射量与骨水泥弥散体积呈正相关;A、C组骨水泥弥散系数随骨水泥注射量的增多而降低,随骨折到手术时间的延长而降低,随术前椎体压缩程度的增大而降低,与骨水泥的黏度无明显相关性。
揹景:椎體成形及椎體後凸成形可有效治療骨質疏鬆性椎體壓縮性骨摺,但兩種手術方式在骨水泥的分佈與瀰散上有差異。<br> 目的:分析骨水泥行椎體成形或後凸成形治療骨質疏鬆椎體壓縮性骨摺後在椎體內瀰散的影響因素。<br> 方法:納入41例骨質疏鬆椎體壓縮性骨摺患者,其中22例進行高黏度骨水泥椎體成形治療(A組),5例進行高黏度骨水泥椎體後凸成形治療(B組),14例進行低黏度骨水泥椎體成形治療(C組)。再根據骨水泥註射量、骨摺至手術時間、術前椎體壓縮程度將A、C組進行亞組分析。通過CT三維成像和容積再現分析骨水泥在椎體內的分佈及瀰散。<br> 結果與結論:3組術後骨水泥在椎體內的相對瀰散麵積及相對瀰散體積無明顯區彆,均能較好地瀰散到上下椎闆併越過椎體中線。3組骨水泥瀰散繫數差異無顯著性意義。在一定範圍內,骨水泥註射量與骨水泥瀰散體積呈正相關;A、C組骨水泥瀰散繫數隨骨水泥註射量的增多而降低,隨骨摺到手術時間的延長而降低,隨術前椎體壓縮程度的增大而降低,與骨水泥的黏度無明顯相關性。
배경:추체성형급추체후철성형가유효치료골질소송성추체압축성골절,단량충수술방식재골수니적분포여미산상유차이。<br> 목적:분석골수니행추체성형혹후철성형치료골질소송추체압축성골절후재추체내미산적영향인소。<br> 방법:납입41례골질소송추체압축성골절환자,기중22례진행고점도골수니추체성형치료(A조),5례진행고점도골수니추체후철성형치료(B조),14례진행저점도골수니추체성형치료(C조)。재근거골수니주사량、골절지수술시간、술전추체압축정도장A、C조진행아조분석。통과CT삼유성상화용적재현분석골수니재추체내적분포급미산。<br> 결과여결론:3조술후골수니재추체내적상대미산면적급상대미산체적무명현구별,균능교호지미산도상하추판병월과추체중선。3조골수니미산계수차이무현저성의의。재일정범위내,골수니주사량여골수니미산체적정정상관;A、C조골수니미산계수수골수니주사량적증다이강저,수골절도수술시간적연장이강저,수술전추체압축정도적증대이강저,여골수니적점도무명현상관성。
BACKGROUND:Percutaneous vertebroplasty and kyphoplasty are both effective in the treatment of osteoporotic vertebral compression fractures, but different in the distribution and dispersion of bone cement. <br> OBJECTIVE:To analyze the factors affecting the bone cement dispersion within the vertebral body in treatment of osteoporotic vertebral compression fracture with vertebroplasty or kyphoplasty. <br> METHODS:A total of 41 patients with osteoporotic vertebral compression fractures were included, and divided into three groups:group A (22 cases receiving high viscosity bone cement vertebroplasty treatment), group B (5 cases receiving high viscosity bone cement kyphoplasty), group C (14 cases receiving low viscosity bone cement vertebroplasty treatment). The groups A and C were divided into subgroups according to bone cement injection volume, time from fracture to operation, preoperative degree of vertebral compression. The distribution and dispersion of bone cement in the vertebra were reconstructed by the CT three-dimensional imaging and volume rendering analysis. <br> RESULTS AND CONCLUSION:In the three groups, after operation, relative dispersion area and relative dispersion volume in the vertebrae had no obvious difference, and the bone cement could al diffuse to upper and lower lamina cross the vertebral midline. There was no significant difference in bone cement diffusion coefficient among the three groups. In a certain range, the bone cement injection volume and bone cement dispersion volume was positively correlated. In groups A and C, bone cement diffusion coefficient decreased with the increasing of bone cement injection volume, time from fracture to operation, and the compression degree of the fractured vertebrae, but showed no significant correlation with bone cement viscosity.