CAJ | 학술논문

　　目的：评价脑梗死后认知功能损害与血尿酸水平的关联性。方法：纳入脑梗死患者211例，根据蒙特利尔认知评估量表(MoCA)测评判断有无认知损害，比较有(无)认知损伤患者血尿酸水平的差异，同时根据血尿酸水平，进行高尿酸血症患者与非高尿酸血症患者发生认知功能损害的相对危险度评价。结果：无认知损害与有认知损害患者血尿酸水平差异无统计学意义；高尿酸血症患者相对于非高尿酸血症患者发生脑梗死后认知功能损害的相对危险度为1.31，95%(1.16，1.47)。结论：脑梗死后存在高尿酸血症患者认知功能损害危险性增高。
　　목적：평개뇌경사후인지공능손해여혈뇨산수평적관련성。방법：납입뇌경사환자211례，근거몽특리이인지평고량표(MoCA)측평판단유무인지손해，비교유(무)인지손상환자혈뇨산수평적차이，동시근거혈뇨산수평，진행고뇨산혈증환자여비고뇨산혈증환자발생인지공능손해적상대위험도평개。결과：무인지손해여유인지손해환자혈뇨산수평차이무통계학의의；고뇨산혈증환자상대우비고뇨산혈증환자발생뇌경사후인지공능손해적상대위험도위1.31，95%(1.16，1.47)。결론：뇌경사후존재고뇨산혈증환자인지공능손해위험성증고。
Objective:To assess the correlation between cognitive impairment and level of blood uric acid in patients after cerebral infarction. Methods:Two hundred and twenty-one patients with cerebral infarc-tion were enrolled and divided into normal cognitive group and cognitive impairment group according to the scores of Montreal Cognitive Assessment (MoCA). The difference of blood uric acid between two groups was compared. The relative risk of cognitive impairment in patients with and without hyper-uricemia was assessed. Results:There was no significant difference of blood uric acid level between the normal cognitive group and cognitive impairment group. The relative risk of patients with hyperuricemia to those without hyperuricemia was 1.31;and 95%confidence interval was 1.16 to 1.47. Conclusion:Hy-peruricemia increases the risk of cognitive impairment in cerebral infarction patients.