CAJ | 학술논문

　　目的：探讨脑卒中合并卵圆孔未闭(PFO)患者的临床特征。方法：回顾性分析2002年1月~2012年11月我院收治的及万方数据库和中国医知网报道的脑卒中合并PFO患者41例的临床资料。结果：本组患者年龄<55岁35例(85.4%)，有少量吸烟史9例，高血压5例，高血脂1例，糖尿病2例；左侧大隐静脉瓣膜功能不全1例，下肢深静脉血栓6例，髋关节置换术后2例；卵圆孔缺损直径≥2 mm者26例(86.7%)；头颅MRI示皮质下白质额叶区、顶叶区梗死各12例。结论：脑卒中合并PFO患者发病年龄偏小，多无常规脑血管病危险因素，卵圆孔缺损直径≥2 mm易发病，确诊需经食管超声心动图、经颅多普勒超声造影等辅助检查。
　　목적：탐토뇌졸중합병란원공미폐(PFO)환자적림상특정。방법：회고성분석2002년1월~2012년11월아원수치적급만방수거고화중국의지망보도적뇌졸중합병PFO환자41례적림상자료。결과：본조환자년령<55세35례(85.4%)，유소량흡연사9례，고혈압5례，고혈지1례，당뇨병2례；좌측대은정맥판막공능불전1례，하지심정맥혈전6례，관관절치환술후2례；란원공결손직경≥2 mm자26례(86.7%)；두로MRI시피질하백질액협구、정협구경사각12례。결론：뇌졸중합병PFO환자발병년령편소，다무상규뇌혈관병위험인소，란원공결손직경≥2 mm역발병，학진수경식관초성심동도、경로다보륵초성조영등보조검사。
Objective:To study the clinical characteristics of stroke patients with patent foramen ovale (PFO). Methods:The clinical data of 41 cases with stroke combined PFO were analyzed retrospectively. Results:In 41 cases, 35 (85.4%) cases were younger than 55 years old, 9 cases had history of smoking, 5 cases had hypertension, one had high cholesterol and 2 cases had diabetes. One had the valve insufficien-cy in left great saphenous vein, 6 cases had deep vein thrombosis in legs and 2 cases were after total hip arthroplasty. Twenty-six cases (86.7%) showed the PFO size larger than 2 mm. Each of 12 cases showed subcortical lesions in the frontal or parietal lobes on brain MRI. Conclusion:Stroke patients with PFO are young (<55 years) and most of them had no risk factors for cerebrovascular diseases. Patients with PFO larger than 2 mm have a higher prevalence of strokes. The transesophageal echocardiography or con-trast-enhanced transcranial color doppler are necessary for the diagnosis.