中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
44期
7122-7126
,共5页
米东%杨明坤%张旭%吴继生%刘川%李舟%王杰
米東%楊明坤%張旭%吳繼生%劉川%李舟%王傑
미동%양명곤%장욱%오계생%류천%리주%왕걸
植入物%脊柱植入物%峡部裂%滑脱%椎间融合器%椎弓根螺钉%内固定
植入物%脊柱植入物%峽部裂%滑脫%椎間融閤器%椎弓根螺釘%內固定
식입물%척주식입물%협부렬%활탈%추간융합기%추궁근라정%내고정
背景:峡部裂性腰椎滑脱主要依靠手术治疗,治疗方式多种多样,但其目的是对病变节段进行减压、复位、固定、融合,治疗金标准为生物性融合,而内固定是融合治疗可靠的辅助方法。<br> 目的:观察椎弓根螺钉系统内固定联合椎间融合器修复峡部裂性腰椎滑脱症的临床疗效。<br> 方法:2010年3月至2013年3月应用椎弓根螺钉系统联合椎间融合器治疗峡部裂性腰椎滑脱症21例,其中Ⅱ度滑脱18例,Ⅲ度滑脱3例。对所有病例进行定期随访,以JOA评分及目测类比评分作为治疗后随访的客观疼痛评价标准,采用Macrab标准评定疗效,根据Prolo指标评价功能恢复,按Lenke标准评估脊柱融合率,通过影像学资料评估滑脱率、滑脱角、骶骨倾斜角和椎间隙后高在治疗前后的改变。<br> 结果与结论:21例腰椎峡部裂性滑脱患者均获随访,随访时间12-16个月。所有患者JOA腰腿痛评分及腰腿痛目测类比评分均较治疗前改善,差异有显著性意义(P=0.000)。根据 Macrab 标准评定,本组优17例,良4例。Prolo活动、症状分级评价治疗前后比较差异有显著性意义(P=0.003)。治疗后腰椎滑脱基本复位,滑脱角明显减少,骶骨倾斜角增大,椎间隙高度基本恢复。提示椎弓根螺钉系统内固定联合椎间融合器是治疗峡部裂性腰椎滑脱症的有效策略之一。
揹景:峽部裂性腰椎滑脫主要依靠手術治療,治療方式多種多樣,但其目的是對病變節段進行減壓、複位、固定、融閤,治療金標準為生物性融閤,而內固定是融閤治療可靠的輔助方法。<br> 目的:觀察椎弓根螺釘繫統內固定聯閤椎間融閤器脩複峽部裂性腰椎滑脫癥的臨床療效。<br> 方法:2010年3月至2013年3月應用椎弓根螺釘繫統聯閤椎間融閤器治療峽部裂性腰椎滑脫癥21例,其中Ⅱ度滑脫18例,Ⅲ度滑脫3例。對所有病例進行定期隨訪,以JOA評分及目測類比評分作為治療後隨訪的客觀疼痛評價標準,採用Macrab標準評定療效,根據Prolo指標評價功能恢複,按Lenke標準評估脊柱融閤率,通過影像學資料評估滑脫率、滑脫角、骶骨傾斜角和椎間隙後高在治療前後的改變。<br> 結果與結論:21例腰椎峽部裂性滑脫患者均穫隨訪,隨訪時間12-16箇月。所有患者JOA腰腿痛評分及腰腿痛目測類比評分均較治療前改善,差異有顯著性意義(P=0.000)。根據 Macrab 標準評定,本組優17例,良4例。Prolo活動、癥狀分級評價治療前後比較差異有顯著性意義(P=0.003)。治療後腰椎滑脫基本複位,滑脫角明顯減少,骶骨傾斜角增大,椎間隙高度基本恢複。提示椎弓根螺釘繫統內固定聯閤椎間融閤器是治療峽部裂性腰椎滑脫癥的有效策略之一。
배경:협부렬성요추활탈주요의고수술치료,치료방식다충다양,단기목적시대병변절단진행감압、복위、고정、융합,치료금표준위생물성융합,이내고정시융합치료가고적보조방법。<br> 목적:관찰추궁근라정계통내고정연합추간융합기수복협부렬성요추활탈증적림상료효。<br> 방법:2010년3월지2013년3월응용추궁근라정계통연합추간융합기치료협부렬성요추활탈증21례,기중Ⅱ도활탈18례,Ⅲ도활탈3례。대소유병례진행정기수방,이JOA평분급목측류비평분작위치료후수방적객관동통평개표준,채용Macrab표준평정료효,근거Prolo지표평개공능회복,안Lenke표준평고척주융합솔,통과영상학자료평고활탈솔、활탈각、저골경사각화추간극후고재치료전후적개변。<br> 결과여결론:21례요추협부렬성활탈환자균획수방,수방시간12-16개월。소유환자JOA요퇴통평분급요퇴통목측류비평분균교치료전개선,차이유현저성의의(P=0.000)。근거 Macrab 표준평정,본조우17례,량4례。Prolo활동、증상분급평개치료전후비교차이유현저성의의(P=0.003)。치료후요추활탈기본복위,활탈각명현감소,저골경사각증대,추간극고도기본회복。제시추궁근라정계통내고정연합추간융합기시치료협부렬성요추활탈증적유효책략지일。
BACKGROUND:The main treatment of lumbar isthmic spondylolisthesis is the surgery, in a broader attempt to decompression, reduction, fixation and fusion of the lesioned segments. The golden standard of the treatment is biological fusion, while internal fixation is a reliable assistance for fusion therapy. <br> OBJECTIVE:To discuss the clinical value and curative effect of intervertebral fusion cage combined with pedicle screw systems for the treatment of lumbar isthmic spondylolisthesis. <br> METHODS:From March 2010 to March 2013, 21 cases of isthmic spondylolisthesis were treated with intervertebral fusion cage combined with pedicle screw systems, including 18 cases of spondylolisthesis of degree II and 3 cases of spondylolisthesis of degree III. Al patients were fol owed up regularly, taking JOA lumbago score and visual analog scale score as the objective evaluation criteria of pain in postoperative fol ow-ups. The curative effect was assessed by Macrab standard, and the functional recovery was evaluated based on indicators such as Prolo, and the spinal fusion rate was assessed according to Lenke criteria. Changes of slippage rate, slippage angle, sacral inclination angle and intervertebral space post height in preoperative and postoperative periods were evaluated by iconography data. <br> RESULTS AND CONCLUSION:Al the 21 patients with isthmic spondylolisthesis were fol owed up for 12-16 months. JOA lumbago score and vasual analog scale score of al patients were improved after treatment, and the difference was statistical y significant compared with before treatment (P=0.000). According to Macrab evaluation criteria, there were 17 excellent cases and 4 good cases. Each indicator evaluated by preoperative Prolo activities and symptom grading showed significant differences in preoperative and postoperative periods (P=0.003). Postoperative lumbar spondylolisthesis was basical y reset, the slippage angle was significantly reduced, the sacral inclination angle was increased, and the height of the intervertebral space was recovered basical y. Intervertebral fusion cage combined with pedicle screw systems was one of the effective strategies to treat lumbar isthmic spondylolisthesis.