健康之路
健康之路
건강지로
HEALTH
2013年
7期
124-124
,共1页
食管癌%三维适形放射治疗%热疗
食管癌%三維適形放射治療%熱療
식관암%삼유괄형방사치료%열료
Esophageal cancer%Three dimensional conformal radiotherapy%Heat treatment
目的:观察三维适形放疗联合热疗对食管鳞癌的近期疗效,与单纯放疗作比较。方法:60例食管癌患者随机分为2组进行观察,单纯放疗(RT)组30例,放疗采用三维适形放射治疗,2Gy/次,5次/周,总剂量66~70Gy/6.5~7周,放疗+热疗(R+ H)组30例,放疗方式同单纯放疗组,同时配合热疗,每周2次,每次加热45分钟,治疗功率80~100W ,共8~10次。结果:近期疗效情况比较,完全缓解(CR),部分缓解(PR),总有效率(CR+ PR)分别为R+ H 组46.7%(14/30),46.7%(14/30),93.3%(28/30);RT 组为33.3%(10/30),36.7%(11/30),70%(21/30),两者之间差异有显著性意义(X2=5.45,P<0.05)。结论:三维适形放射治疗联合热疗明显优于单纯放疗组,热疗对肿瘤细胞有一定的杀伤作用,提高放射敏感性,可明显提高食管癌的局部控制率,减少复发率,进一步提高了患者的生活质量。
目的:觀察三維適形放療聯閤熱療對食管鱗癌的近期療效,與單純放療作比較。方法:60例食管癌患者隨機分為2組進行觀察,單純放療(RT)組30例,放療採用三維適形放射治療,2Gy/次,5次/週,總劑量66~70Gy/6.5~7週,放療+熱療(R+ H)組30例,放療方式同單純放療組,同時配閤熱療,每週2次,每次加熱45分鐘,治療功率80~100W ,共8~10次。結果:近期療效情況比較,完全緩解(CR),部分緩解(PR),總有效率(CR+ PR)分彆為R+ H 組46.7%(14/30),46.7%(14/30),93.3%(28/30);RT 組為33.3%(10/30),36.7%(11/30),70%(21/30),兩者之間差異有顯著性意義(X2=5.45,P<0.05)。結論:三維適形放射治療聯閤熱療明顯優于單純放療組,熱療對腫瘤細胞有一定的殺傷作用,提高放射敏感性,可明顯提高食管癌的跼部控製率,減少複髮率,進一步提高瞭患者的生活質量。
목적:관찰삼유괄형방료연합열료대식관린암적근기료효,여단순방료작비교。방법:60례식관암환자수궤분위2조진행관찰,단순방료(RT)조30례,방료채용삼유괄형방사치료,2Gy/차,5차/주,총제량66~70Gy/6.5~7주,방료+열료(R+ H)조30례,방료방식동단순방료조,동시배합열료,매주2차,매차가열45분종,치료공솔80~100W ,공8~10차。결과:근기료효정황비교,완전완해(CR),부분완해(PR),총유효솔(CR+ PR)분별위R+ H 조46.7%(14/30),46.7%(14/30),93.3%(28/30);RT 조위33.3%(10/30),36.7%(11/30),70%(21/30),량자지간차이유현저성의의(X2=5.45,P<0.05)。결론:삼유괄형방사치료연합열료명현우우단순방료조,열료대종류세포유일정적살상작용,제고방사민감성,가명현제고식관암적국부공제솔,감소복발솔,진일보제고료환자적생활질량。
Objective :Observing the recent efficacy of the patients with esophageal squamous cell carcinomas ,who were treated with three dimen-sional conformal radiotherapy combined with heat treatment ,compared to radiotherapy alone .Methods :60 patients with esophageal cancer were ran-domly divided into two groups ,One group wsa pure radiation therapy (RT) group with 30 cases ,treated with three dimensional conformal radiation therapy only ,2Gy/f ,5f/W ,the total dose 66 ~ 70 Gy /6 .5 ~ 7 weeks .The control group was treated with radiotherapy combined with heat treatment with 30 cases (R + H) .The Radiotherapy of the two groups was in the same way .In the control group ,heat treatment treated for 45 min/f ,2 times a week ,and the treatment power of 80 ~ 100 w ,a total of 8 ~ 10 times .Result:The recent curative effect ,Complete response (CR) ,partial response (PR) ,the total effective rate (CR + PR) of R + H group was 46 .7% (14/30) ,46 .7% (14/30) ,93 .3% (28/30);RT group was 33 .3% (10/30) ,33 .3% (11/30) ,70% (21/30) .There was significant difference between two groups (X2 = 5 .45 ,P< 0 .05) .Conclu-sion:The curative effect of three dimensional conformal radiotherapy combined with heat treatment was better than simple radiotherapy group .Heat treatment has certain killing effect on the tumor cells ,and it could improve the radiotherapy sensitivity .Heat treatment could obviously improve the local control rates of esophageal cancer and reduce the recurrence rate .So it could further improve the patient's quality of life .