化学研究与应用
化學研究與應用
화학연구여응용
CHEMICAL RESEARCH AND APPLICATION
2013年
7期
1046-1049
,共4页
罗再刚%马超%徐雪梅%张晓梅
囉再剛%馬超%徐雪梅%張曉梅
라재강%마초%서설매%장효매
杯4芳烃%α,γ-二酮%合成
杯4芳烴%α,γ-二酮%閤成
배4방경%α,γ-이동%합성
calix[4] arene%α,γ-diketo%synthesis
以对叔丁基杯[4]芳烃为原料脱除叔丁基得到杯[4]芳烃,再经醚化、缩合两步反应首次合成25,27-二(α,γ-二酮苯丁氧基)-26,28-二羟基杯[4]芳烃,其结构经1 H NMR、13 C NMR、MS及元素分析表征。研究表明,目标化合物中的α,γ-二酮结构存在酮醇异构现象,在溶液中其酮醇异构体比例近似为1∶2。
以對叔丁基杯[4]芳烴為原料脫除叔丁基得到杯[4]芳烴,再經醚化、縮閤兩步反應首次閤成25,27-二(α,γ-二酮苯丁氧基)-26,28-二羥基杯[4]芳烴,其結構經1 H NMR、13 C NMR、MS及元素分析錶徵。研究錶明,目標化閤物中的α,γ-二酮結構存在酮醇異構現象,在溶液中其酮醇異構體比例近似為1∶2。
이대숙정기배[4]방경위원료탈제숙정기득도배[4]방경,재경미화、축합량보반응수차합성25,27-이(α,γ-이동분정양기)-26,28-이간기배[4]방경,기결구경1 H NMR、13 C NMR、MS급원소분석표정。연구표명,목표화합물중적α,γ-이동결구존재동순이구현상,재용액중기동순이구체비례근사위1∶2。
25,27-Di(α,γ-diketophenylbutoxy)-26,28-dihydroxy calix[4]arene was synthesized by a two-step reaction of etherifica-tion and condensation from calix [4] arene,which was prepared by p-tert-butylcalyx [4] arene as the raw material via dealkyla-tion.The structure of title compound was characterized by 1 H NMR,13 C NMR,MS and elemental analysis.The results also indicated that keto-enol tautomerism of the α,γ-diketo motif of the title compound was observed and the ratio of the keto-enol isomer approxi-mately was 1:2.