CAJ | 학술논문

　　本文设计并合成了两个含手性边臂的β-环糊精衍生物，在水溶液中它们与钌形成配合物，该配合物成功的将1-（9′-嘌呤基）-2-丙酮还原得到1-（9′-嘌呤基）-2-丙醇。反应给出了高的分离产率和一定的对映体选择性，为核苷类化合物的合成提供了新的思路。
　　본문설계병합성료량개함수성변비적β-배호정연생물，재수용액중타문여조형성배합물，해배합물성공적장1-（9′-표령기）-2-병동환원득도1-（9′-표령기）-2-병순。반응급출료고적분리산솔화일정적대영체선택성，위핵감류화합물적합성제공료신적사로。
Two β-cyclodextrin derivatives with chiral side-arm were synthesized .Their complexes with Ru in aqueous were formed and could reduce 1-(9H-purin-9-yl)propan-2-one into 1-(9H-purin-9-yl)propan-2-ol efficiently,giving excellent separation yields and low enantioselectivity .It was the first report on the application of β-cyclodextrin derivative as assistant in the synthesis of chiral acyclic nucleosides ,providing a new approach to obtain nucleosides.