中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2013年
9期
46-49
,共4页
金保方%张新东%王志强%林树栋%杨晓玉%夏国守%孙大林%高永金%唐志安%李相如%翟振彦
金保方%張新東%王誌彊%林樹棟%楊曉玉%夏國守%孫大林%高永金%唐誌安%李相如%翟振彥
금보방%장신동%왕지강%림수동%양효옥%하국수%손대림%고영금%당지안%리상여%적진언
少精子症%弱精子症%龙鹿胶囊
少精子癥%弱精子癥%龍鹿膠囊
소정자증%약정자증%룡록효낭
oligospermia%asthenozoospermia%Longlu Capsule
目的：观察龙鹿胶囊治疗少弱精子症的疗效，并探讨其可能的作用机制。方法采用多中心、随机对照的临床研究，将确诊的360例患者随机分为对照组（160例）和治疗组（200例）。对照组服用VitE，100mg，bid；治疗组服用龙鹿胶囊，3粒，tid。两组治疗3个月后，分别检测精液质量（精液量、精子浓度、前向运动精子、精子DFI、精浆SOD）及女方受孕率。结果有330例患者完成了临床研究，治疗组在精液量、精子浓度、前向运动精子、精子DFI、精浆SOD方面较用药前，均有显著的改善（P＜0.05），并且疗效优于对照组（P＜0.05）。结论龙鹿胶囊可提高体内的抗氧化能力，改善精子质量及自然妊娠率，并未见明显不良反应。
目的：觀察龍鹿膠囊治療少弱精子癥的療效，併探討其可能的作用機製。方法採用多中心、隨機對照的臨床研究，將確診的360例患者隨機分為對照組（160例）和治療組（200例）。對照組服用VitE，100mg，bid；治療組服用龍鹿膠囊，3粒，tid。兩組治療3箇月後，分彆檢測精液質量（精液量、精子濃度、前嚮運動精子、精子DFI、精漿SOD）及女方受孕率。結果有330例患者完成瞭臨床研究，治療組在精液量、精子濃度、前嚮運動精子、精子DFI、精漿SOD方麵較用藥前，均有顯著的改善（P＜0.05），併且療效優于對照組（P＜0.05）。結論龍鹿膠囊可提高體內的抗氧化能力，改善精子質量及自然妊娠率，併未見明顯不良反應。
목적：관찰룡록효낭치료소약정자증적료효，병탐토기가능적작용궤제。방법채용다중심、수궤대조적림상연구，장학진적360례환자수궤분위대조조（160례）화치료조（200례）。대조조복용VitE，100mg，bid；치료조복용룡록효낭，3립，tid。량조치료3개월후，분별검측정액질량（정액량、정자농도、전향운동정자、정자DFI、정장SOD）급녀방수잉솔。결과유330례환자완성료림상연구，치료조재정액량、정자농도、전향운동정자、정자DFI、정장SOD방면교용약전，균유현저적개선（P＜0.05），병차료효우우대조조（P＜0.05）。결론룡록효낭가제고체내적항양화능력，개선정자질량급자연임신솔，병미견명현불량반응。
Objective To observe the efficacy of Longlu Capsule in the treatment of oligoasthenospermia and explore its probable mechanism. Methods Usig the multi-centered randomized controlled study, 360 infertile men with oligoasthenospermia were divided into two groups including the control group (160 cases) and the treatment group (200 cases). The patients in the control group were administrated VitE, 100mg once, bid and the patients in the treatment group were given Longlu Capsule, three pills, tid. After the treatment for 3 months, Semen volume, spermatozoa density, prorsad spermatozoa rate, spermatozoa DFI, seminal SOD, and pregnancy rate were measured. Results A total of 330 patients accomplished the clinical trial. In the treatment group, the index of semen volume, spermatozoa density, prorsad spermatozoa rate, spermatozoa DFI, and seminal SOD, were obviously improved compared to that of pre-treatment (P<0.05). Meanwhile, an obvious amelioration in spermatozoa density, prorsad spermatozoa rate, spermatozoa DFI, seminal SOD, and pregnancy rate were found compared to that of the control group (P<0.05). Conclusion Longlu Capsule can evidently improve the seminal quality and natural pregnancy rate of oligoasthenospermia patients via increasing the anti-oxidant ability.
