CAJ | 학술논문

目的：分析艾迪注射液联合髂内动脉化疗（观察组）与单纯髂内动脉化疗（对照组）对浸润性膀胱癌的疗效、毒副反应及对免疫功能的影响。方法观察组36例浸润性膀胱癌患者在采用髂内动脉化疗同期加用艾迪注射液，对照组30例浸润性膀胱癌患者单用髂内动脉化疗。结果观察组有效率为38．9％高于对照组26．9％，差异有统计学意义（P＜0．05）。观察组治疗前后免疫功能的改变、毒副反应、胃肠反应均明显低于对照组，差异有统计学意义（P＜0．05）。结论艾迪联合髂内动脉化疗治疗浸润性膀胱癌，疗效显著，并降低了髂内动脉化疗方案对免疫功能、胃肠道的影响及毒副反应，此种方法可以作为不能手术切除的浸润性膀胱癌的治疗。
목적：분석애적주사액연합가내동맥화료（관찰조）여단순가내동맥화료（대조조）대침윤성방광암적료효、독부반응급대면역공능적영향。방법관찰조36례침윤성방광암환자재채용가내동맥화료동기가용애적주사액，대조조30례침윤성방광암환자단용가내동맥화료。결과관찰조유효솔위38．9％고우대조조26．9％，차이유통계학의의（P＜0．05）。관찰조치료전후면역공능적개변、독부반응、위장반응균명현저우대조조，차이유통계학의의（P＜0．05）。결론애적연합가내동맥화료치료침윤성방광암，료효현저，병강저료가내동맥화료방안대면역공능、위장도적영향급독부반응，차충방법가이작위불능수술절제적침윤성방광암적치료。
Objective To analyze Addie injection combined with intra arterial chemotherapy (observation group) and simple internal iliac arterial chemotherapy (control group) effect on invasive bladder cancer ,toxicity and immune function of .Methods in the observation group , 36 cases of invasive bladder cancer patients in the internal iliac artery chemotherapy concurrent with Addie injection ,the control group of 30 patients with invasive bladder cancer patients with single Yongqia arterial chemotherapy .Results the observation group was 38 .9% higher than that of the control group 26 .9% ,the difference was statistically significant (P<0 .05) .Observation of immune function before and after treatment ,the changes of toxicity ,gastrointestinal reaction were significantly lower than the control group ,the difference was statistically significant (P< 0 .05 ) .Conclusion Addie combined with internal iliac artery chemotherapy for invasive bladder cancer , obvious curative effect ,and reduce the toxicity and effect of internal iliac arterial chemotherapy on immune function ,the gastrointestinal tract ,this method can be used as not operation resection of invasive bladder cancer .