CAJ | 학술논문

目的：探讨新生儿恶性心律失常的病因、临床特征及转归。方法回顾性分析2005年1月至2010年1月诊断的27例恶性心律失常新生儿的临床资料。结果27例患儿中，男15例，女12例；早期新生儿14例，晚期新生儿13例；胎龄≤32周6例，>32周21例。19例快速性心律失常新生儿中，呼吸道感染14例；8例缓慢性心律失常新生儿中，先天性心脏病3例，电解质紊乱2例，重度窒息合并败血症2例，重度窒息1例。缓慢性心律失常新生儿的发病日龄、胎龄明显小于快速性心律失常新生儿，差异有统计学意义（P均<0.005）。快速性心律失常治愈率89.5%，有效率100%；而缓慢性心律失常治愈率为0%，有效率12.5%，差异有统计学意义（P均<0.005）。结论新生儿快速性心律失常与缓慢性心律失常临床特征及发病机制各不相同，预后差异大。
목적：탐토신생인악성심률실상적병인、림상특정급전귀。방법회고성분석2005년1월지2010년1월진단적27례악성심률실상신생인적림상자료。결과27례환인중，남15례，녀12례；조기신생인14례，만기신생인13례；태령≤32주6례，>32주21례。19례쾌속성심률실상신생인중，호흡도감염14례；8례완만성심률실상신생인중，선천성심장병3례，전해질문란2례，중도질식합병패혈증2례，중도질식1례。완만성심률실상신생인적발병일령、태령명현소우쾌속성심률실상신생인，차이유통계학의의（P균<0.005）。쾌속성심률실상치유솔89.5%，유효솔100%；이완만성심률실상치유솔위0%，유효솔12.5%，차이유통계학의의（P균<0.005）。결론신생인쾌속성심률실상여완만성심률실상림상특정급발병궤제각불상동，예후차이대。
Objective To discuss the etiology, clinical features and prognosis of non benign neonatal arrhythmias. Method Clinical data of 27 cases of non benign neonatal arrhythmias diagnosed from January 2005 to January 2010 were retrospectively analyzed. Results Among 27 neonats, there were 15 male and 12 female. Fourteen cases were early neonatal and 13 were late neonatal. Gestational age was less than 32 weeks in 6 cases, and more than 32 weeks in 21 cases. In 19 cases with tachyarrhythmia, 14 cases were induced by respiratory infection. The causes of 8 newborns with bradycardia arrhythmia were congenital heart disease (3 cases), electrolyte disturbance (2 cases), severe asphyxia with sepsis (2 cases), and severe asphyxia (1 case). The onset age and gestational age were lower in cases with bradycardia arrhythma that those in cases with tachyarrhythmia (P<0.005). The cure rate and effective rate of tachyarrhythmia was 89.5%and 100%, of bradycardia arrhythmia was 0%and 12.5%, respectively, and the differences were signiifcant (P<0.005). Conclusion Clinical characteristics, pathogenesis and prognosis were different between tachyarrhythmia and bradycardia arrhythmia in neonates.