CAJ | 학술논문

目的：比较利福平胶囊和利福平注射液治疗肺结核的临床疗效。方法：120例肺结核患者分为观察组和对照组，每组60例，两组患者均采用2HRZE/4HR标准化疗方案治疗，观察组给予利福平注射液治疗，对照组给予利福平胶囊治疗。结果：疗程结束时观察组和对照组痰菌阴转率分别为91.7%、78.3%；病灶吸收率分别为86.7%、61.7%，两组比较差异均有统计学意义(P<0.05)。两组空洞闭合、缩小例数及不良反应发生率比较差异均无统计学意义(P>0.05)。结论：利福平注射液治疗肺结核疗效显著，副作用小，有较好的临床应用价值。
목적：비교리복평효낭화리복평주사액치료폐결핵적림상료효。방법：120례폐결핵환자분위관찰조화대조조，매조60례，량조환자균채용2HRZE/4HR표준화료방안치료，관찰조급여리복평주사액치료，대조조급여리복평효낭치료。결과：료정결속시관찰조화대조조담균음전솔분별위91.7%、78.3%；병조흡수솔분별위86.7%、61.7%，량조비교차이균유통계학의의(P<0.05)。량조공동폐합、축소례수급불량반응발생솔비교차이균무통계학의의(P>0.05)。결론：리복평주사액치료폐결핵료효현저，부작용소，유교호적림상응용개치。
Objective:To observed and compared the clinical effectiveness of pulmonary tuberculosis curing by rifampicin caps and rifampicin injection. Method:One hundred and twenty cases of pulmonary tuberculosis patients were divided into the observation group(n=60) and the control group(n=60),all the cases were treated with 2HREZ/4HR standard chemotherapy formula. The observation group were treated by Rifampicin Injection during the intensify phase,while the control group were treated by taking Rifampicin Capsules. Result:The sputum negative conversion rates were 91.7%and 78.3%in the observation group and the control group respectively,and the lesions absorption rates of two groups were 86.7%and 61.7%respectively,and the difference between the two groups were all statistically significant(P<0.05). It had no significant difference between two groups with the hole closed and narrow cases,incidence of adverse reactions. Conclusion:Rifampicin injection has a good curative effect in treating pulmonary tuberculosis,which fewer adverse reactions. It is of great value in the clinical practice.