临床儿科杂志
臨床兒科雜誌
림상인과잡지
2013年
11期
1029-1033
,共5页
蔡利红%季伟%孙慧明%李蓓荃%严永东%黄莉%陈正荣%闻芳%邵雪军%朱宏
蔡利紅%季偉%孫慧明%李蓓荃%嚴永東%黃莉%陳正榮%聞芳%邵雪軍%硃宏
채리홍%계위%손혜명%리배전%엄영동%황리%진정영%문방%소설군%주굉
肺炎%细菌%耐药性%儿童
肺炎%細菌%耐藥性%兒童
폐염%세균%내약성%인동
pneumonia%bacterial pathogen%antibiotic resistance%child
目的：了解苏州地区住院肺炎患儿咽部常见定植菌情况并分析其耐药性。方法对2005年10月-2011年9月苏州地区因肺炎住院患儿8179例，采用无菌负压吸引法采集新鲜痰液标本进行细菌培养，对检出细菌用纸片扩散法（K-B法）和肉汤稀释法分析其对抗生素的耐药性。结果8179例患儿中细菌检测阳性2391例，阳性率为29.23%。共检出细菌2552株，检出率前五位依次是肺炎链球菌（42.40%）、流感嗜血杆菌（14.81%）、卡他莫拉菌（11.01%）、金黄色葡萄球菌（8.50%）、大肠埃希菌（5.02%）。不同年龄、季节、类型肺炎患儿的咽部常见定植菌的差异有统计学意义（P均<0.001）。2140株细菌进行药敏试验，各细菌耐药率均呈上升趋势。结论苏州地区肺炎患儿最常见的咽部定植菌是肺炎链球菌和流感嗜血杆菌，细菌分布与年龄、季节及肺炎类型有关，需监测细菌并合理用药，以减少耐药菌株的产生。[临床儿科杂志,2013,31(11)：1029-1033]
目的：瞭解囌州地區住院肺炎患兒嚥部常見定植菌情況併分析其耐藥性。方法對2005年10月-2011年9月囌州地區因肺炎住院患兒8179例，採用無菌負壓吸引法採集新鮮痰液標本進行細菌培養，對檢齣細菌用紙片擴散法（K-B法）和肉湯稀釋法分析其對抗生素的耐藥性。結果8179例患兒中細菌檢測暘性2391例，暘性率為29.23%。共檢齣細菌2552株，檢齣率前五位依次是肺炎鏈毬菌（42.40%）、流感嗜血桿菌（14.81%）、卡他莫拉菌（11.01%）、金黃色葡萄毬菌（8.50%）、大腸埃希菌（5.02%）。不同年齡、季節、類型肺炎患兒的嚥部常見定植菌的差異有統計學意義（P均<0.001）。2140株細菌進行藥敏試驗，各細菌耐藥率均呈上升趨勢。結論囌州地區肺炎患兒最常見的嚥部定植菌是肺炎鏈毬菌和流感嗜血桿菌，細菌分佈與年齡、季節及肺炎類型有關，需鑑測細菌併閤理用藥，以減少耐藥菌株的產生。[臨床兒科雜誌,2013,31(11)：1029-1033]
목적：료해소주지구주원폐염환인인부상견정식균정황병분석기내약성。방법대2005년10월-2011년9월소주지구인폐염주원환인8179례，채용무균부압흡인법채집신선담액표본진행세균배양，대검출세균용지편확산법（K-B법）화육탕희석법분석기대항생소적내약성。결과8179례환인중세균검측양성2391례，양성솔위29.23%。공검출세균2552주，검출솔전오위의차시폐염련구균（42.40%）、류감기혈간균（14.81%）、잡타막랍균（11.01%）、금황색포도구균（8.50%）、대장애희균（5.02%）。불동년령、계절、류형폐염환인적인부상견정식균적차이유통계학의의（P균<0.001）。2140주세균진행약민시험，각세균내약솔균정상승추세。결론소주지구폐염환인최상견적인부정식균시폐염련구균화류감기혈간균，세균분포여년령、계절급폐염류형유관，수감측세균병합리용약，이감소내약균주적산생。[림상인과잡지,2013,31(11)：1029-1033]
Objectives To investigate the bacterial pathogens and their antibiotic resistance in children with pneumonia in Suzhou area. Methods Sputum specimens of 8179 hospitalized children with pneumonia from October 2005 to September 2011 were collected by sterile negative pressure aspirator and then cultured. The incidence of positive bacteria was tested by Kirby-Bauer method and broth dilution method, and their antibiotics resistances were analyzed. Results A total of 2391 of 8179 children were infected with positive rate of 29.23%. A total of 2552 strains of bacteria were detected with Streptococcus pneumoniae (42.40%), Haemophilus inlfuenzae (14.81%), Moraxelle catarrhalis (11.01%), Staphylococcus aureus (8.50%) and Escherichia coli (5.02%) as the most common strains. The infection rate of different bacterium was related to age, season and the type of pneumonia (all P<0.001). The tendency of antibiotic resistances in 2 140 bacterial isolates was found increased by the susceptibility test. Conclusions Streptococcus pneumonia and Haemophilus inlfuenzae are the most common bacterial pathogens in children with pneumonia in Suzhou area. The positive rate of different bacterium was related to age, season and the type of pneumonia. Attention must be paid to the rational use of antibiotics to reduce drug resistance.
