西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2013年
11期
30-31
,共2页
胡君茹%姜华%李喜香
鬍君茹%薑華%李喜香
호군여%강화%리희향
吐温-80%DMSO%1,2-丙二醇%非水溶性溶剂%抑菌作用
吐溫-80%DMSO%1,2-丙二醇%非水溶性溶劑%抑菌作用
토온-80%DMSO%1,2-병이순%비수용성용제%억균작용
tween-80%DMSO%1,2-propanediol%non-water-soluble solvents%inhibitory activity
目的:考察吐温-80、二甲基亚砜(DMSO)、1,2-丙二醇3种非水溶性物质溶剂,在抑菌试验中溶解非水溶性供试品时对抑菌效果的影响。方法:通过体外抑菌试验,用琼脂扩散法测定3种溶剂的抑菌作用。结果:DMSO与水混合的不同浓度对金黄色葡萄球菌和大肠杆菌均无抑菌作用,在抑菌试验中可用于溶解非水溶性供试品,而吐温-80和1,2-丙二醇对抑菌效果有干扰。结论:在考察非水溶性供试品的抑菌活性时,DMSO对抑菌结果无干扰,可作为适宜的溶剂溶解非水溶性供试品。
目的:攷察吐溫-80、二甲基亞砜(DMSO)、1,2-丙二醇3種非水溶性物質溶劑,在抑菌試驗中溶解非水溶性供試品時對抑菌效果的影響。方法:通過體外抑菌試驗,用瓊脂擴散法測定3種溶劑的抑菌作用。結果:DMSO與水混閤的不同濃度對金黃色葡萄毬菌和大腸桿菌均無抑菌作用,在抑菌試驗中可用于溶解非水溶性供試品,而吐溫-80和1,2-丙二醇對抑菌效果有榦擾。結論:在攷察非水溶性供試品的抑菌活性時,DMSO對抑菌結果無榦擾,可作為適宜的溶劑溶解非水溶性供試品。
목적:고찰토온-80、이갑기아풍(DMSO)、1,2-병이순3충비수용성물질용제,재억균시험중용해비수용성공시품시대억균효과적영향。방법:통과체외억균시험,용경지확산법측정3충용제적억균작용。결과:DMSO여수혼합적불동농도대금황색포도구균화대장간균균무억균작용,재억균시험중가용우용해비수용성공시품,이토온-80화1,2-병이순대억균효과유간우。결론:재고찰비수용성공시품적억균활성시,DMSO대억균결과무간우,가작위괄의적용제용해비수용성공시품。
Objective:To survey the effects of tween-80, dimethyl sulfoxide (DMSO) and 1, 2-propanediol on inhibitory activity in antibacterial test. Method:Inhibitory activity of all the solvents was detected by agar disc diffu-sion method for antibacterial test in vitro. Result:Different concentrations of DMSO mixed liquid showed no inhibi-tion to Staphylococcus aureus and Escherichia coli while Tween 80 and 1, 2-propanediol demonstrated interference to antibacterial results. Conclusion:In the investigation of inhibitory activity of non-water-soluble solvents, DMSO has no interference to antibacterial results and is suitable for dissolving non-water-soluble solvents in antibacterial test.