中国保健营养(上旬刊)
中國保健營養(上旬刊)
중국보건영양(상순간)
China Health Care & Nutrition
2014年
4期
1863-1865
,共3页
卒中%痫性发作%癫痫
卒中%癇性髮作%癲癇
졸중%간성발작%전간
Stroke%Seizure%Epilepsy
目的:探讨卒中后痫性发作与癫痫的临床特点。方法对2003年7月至2008年6月972例连续卒中病例中74例卒中后痫性发作与癫痫患者的临床资料进行回顾性分析。结果卒中后痫性发作发病率为7.6%。缺血性卒中患者出现痫性发作47例(6.8%),其中皮层梗死24例(51.1%),大面积梗死9例(19.1%),皮层下梗死14例(29.8%);颅内出血患者出现痫性发作24例(8.8%),其中皮层出血16例(66.7%),皮层下出血8例(33.3%);蛛网膜下腔出血组3例(30%)。早期痫性发作58例(78.4%),晚期痫性发作16例(21.6%)。42例进行常规脑电图检查,结果:24例未见异常,14例痫样放电,4例阵发性广泛中-高幅慢活动。早期痫性发作患者4例一周内死亡。卒中后癫痫患者中10例和3例分别服药1年和2年后停药无复发;4例持续用药,平均治疗时间2.5年;4例死亡,2例失访。结论卒中病灶部位、范围及卒中类型是卒中后痫性发作的预测因素。晚期痫性发作是卒中后癫痫的危险因素。卒中后痫性发作的诊断主要依靠病史。一些新型抗癫痫药物可作为单药治疗卒中后痫性发作和癫痫的一线选择。
目的:探討卒中後癇性髮作與癲癇的臨床特點。方法對2003年7月至2008年6月972例連續卒中病例中74例卒中後癇性髮作與癲癇患者的臨床資料進行迴顧性分析。結果卒中後癇性髮作髮病率為7.6%。缺血性卒中患者齣現癇性髮作47例(6.8%),其中皮層梗死24例(51.1%),大麵積梗死9例(19.1%),皮層下梗死14例(29.8%);顱內齣血患者齣現癇性髮作24例(8.8%),其中皮層齣血16例(66.7%),皮層下齣血8例(33.3%);蛛網膜下腔齣血組3例(30%)。早期癇性髮作58例(78.4%),晚期癇性髮作16例(21.6%)。42例進行常規腦電圖檢查,結果:24例未見異常,14例癇樣放電,4例陣髮性廣汎中-高幅慢活動。早期癇性髮作患者4例一週內死亡。卒中後癲癇患者中10例和3例分彆服藥1年和2年後停藥無複髮;4例持續用藥,平均治療時間2.5年;4例死亡,2例失訪。結論卒中病竈部位、範圍及卒中類型是卒中後癇性髮作的預測因素。晚期癇性髮作是卒中後癲癇的危險因素。卒中後癇性髮作的診斷主要依靠病史。一些新型抗癲癇藥物可作為單藥治療卒中後癇性髮作和癲癇的一線選擇。
목적:탐토졸중후간성발작여전간적림상특점。방법대2003년7월지2008년6월972례련속졸중병례중74례졸중후간성발작여전간환자적림상자료진행회고성분석。결과졸중후간성발작발병솔위7.6%。결혈성졸중환자출현간성발작47례(6.8%),기중피층경사24례(51.1%),대면적경사9례(19.1%),피층하경사14례(29.8%);로내출혈환자출현간성발작24례(8.8%),기중피층출혈16례(66.7%),피층하출혈8례(33.3%);주망막하강출혈조3례(30%)。조기간성발작58례(78.4%),만기간성발작16례(21.6%)。42례진행상규뇌전도검사,결과:24례미견이상,14례간양방전,4례진발성엄범중-고폭만활동。조기간성발작환자4례일주내사망。졸중후전간환자중10례화3례분별복약1년화2년후정약무복발;4례지속용약,평균치료시간2.5년;4례사망,2례실방。결론졸중병조부위、범위급졸중류형시졸중후간성발작적예측인소。만기간성발작시졸중후전간적위험인소。졸중후간성발작적진단주요의고병사。일사신형항전간약물가작위단약치료졸중후간성발작화전간적일선선택。
Objective To study the clinical features of poststroke seizures and epilepsy .Methods Medical documents of 74 patients with poststroke seizures and epi-lepsy,accounting for 7.6% of 972 consecutive stroke patients from 2003 July to 2008 June,were retrospectively analyzed.Results Seizures were developed in 47 patients with ischemic stroke(6.8%),and in 24 patients with intracerebral hemorrhage(8.8%),and in 3 patients with subarachnoid hemorrhage(30.0%).There were 58 pa-tients with early seizures and 16 patients with late seizures,respectively.Among 47 patients with seizures after ischemic stroke,24 patients suffered from cortical infarct, 14 from subcortical infarct,and 9 from massive infarct.Among 24 patients with seizures after intracerebral hemorrhage ,16 patients suffered from cortical hemorrhage and 8 from subcortical hemorrhage.Routine electroencephalography was performed in 42 patients with seizures,epileptiform discharge was seen in 14 patients,paroxysmal dif-fused slow activity in 4 and the rest 24 patients did not show apparent abnormality.Four patients with early seizures died within 7 days.Ten and 3 patients with poststroke epilepsy got free from seizures after 1 and 2 years of medical treatment,respectively;4 patients keep on medical treatment for an average time of 2.5 years;4 died and 2 lost during follow-up.Conclusion Cortical lesions,massive infarcts and hemorrhagic stroke may be predictors for poststroke seizures .Late poststroke seizure may be a risk factor for poststroke epilepsy.The diagnosis of poststroke seizures was mainly based on an accurate description of manifestation and some new anti -epileptic drugs can be the first-line monotherapy in patients with poststroke seizures and epilepsy .