CAJ | 학술논문

目的：采用气相色谱法测定参苓白术散中樟脑、龙脑、乙酸龙脑酯的含量,并建立其质量标准。方法采用100%甲基聚硅氧烷为固定相的毛细管柱；程序升温：起始温度60℃,以5℃/min升到130℃,保持5 min,续以20℃/min升到230℃,保持5 min。结果樟脑平均回收率为99.87%,RSD＝1.3%,进样量在0.00377～0.1508μg范围内呈良好的线性关系(r＝0.9999)；龙脑平均回收率为100.71%,RSD＝2.1%,进样量在0.002411～0.0964μg范围内呈良好的线性关系(r＝0.9999)；乙酸龙脑酯平均回收率为101.95%,RSD＝1.3%,进样量在0.00302～0.1211μg范围内呈良好的线性关系(r＝0.9999)。结论本方法操作简便,结果可靠、准确,能有效控制参苓白术散中砂仁的质量。
목적：채용기상색보법측정삼령백술산중장뇌、용뇌、을산용뇌지적함량,병건립기질량표준。방법채용100%갑기취규양완위고정상적모세관주；정서승온：기시온도60℃,이5℃/min승도130℃,보지5 min,속이20℃/min승도230℃,보지5 min。결과장뇌평균회수솔위99.87%,RSD＝1.3%,진양량재0.00377～0.1508μg범위내정량호적선성관계(r＝0.9999)；용뇌평균회수솔위100.71%,RSD＝2.1%,진양량재0.002411～0.0964μg범위내정량호적선성관계(r＝0.9999)；을산용뇌지평균회수솔위101.95%,RSD＝1.3%,진양량재0.00302～0.1211μg범위내정량호적선성관계(r＝0.9999)。결론본방법조작간편,결과가고、준학,능유효공제삼령백술산중사인적질량。
Objective To establish a GC method for simultaneous determine of camphor, borneol and bornyl acetate in Shenling Baizhu Powder. Methods Capillary column was used with 100% methyl polysiloxane as stationary phase. The temperature-programmed was as follows:starting temperature of 60 ℃, 5 ℃/min, rose to 130 ℃, kept for 5 minutes, followed by 20 ℃/min up to 230 ℃, and kept for 5 minutes. Results The average recovery rate of camphor was 99.87%, RSD was 1.3%, and good linear relationship was showed in the range of 0.003 77-0.150 8 μg (r=0.999 9). The average recovery of borneol was 100.71%, RSD was 2.1%, and good linear relationship was showed in the range of 0.002 411-0.096 4 μg (r=0.999 9). The average recovery rate of bornyl acetate was 101.95%, RSD was 1.3%, and good linear relationship was showed in the range of 0.003 02-0.121 1 μg (r=0.999 9). Conclusion The method is simple, reliable, accurate, and can effectively control the quality of Amomi Fructus in Shenling Baizhu Powder.