CAJ | 학술논문

目的：探析顽固性溃疡性结肠炎应用硫唑嘌呤治疗的临床效果。方法选取2010年7月至2012年12月在我院进行硫唑嘌呤治疗的50例脑顽固性溃疡性结肠炎患者进行临床研究。结果本组患者治疗有效率为88%，缓解率为76%，红细胞沉降率及 C 反应蛋白有明显下降，比较差异有统计学意义（P ＜0.05），不良反应发生率为30%。结论顽固性溃疡性结肠炎应用硫唑嘌呤治疗效果良好，不良反应少，值得临床推广。
목적：탐석완고성궤양성결장염응용류서표령치료적림상효과。방법선취2010년7월지2012년12월재아원진행류서표령치료적50례뇌완고성궤양성결장염환자진행림상연구。결과본조환자치료유효솔위88%，완해솔위76%，홍세포침강솔급 C 반응단백유명현하강，비교차이유통계학의의（P ＜0.05），불량반응발생솔위30%。결론완고성궤양성결장염응용류서표령치료효과량호，불량반응소，치득림상추엄。
Objective To explore application of refractory ulcerative colitis clinical effect of azathioprine treatment. Methods From 2010 July to 2012 December in our hospital 50 cases of cerebral patients with intractable ulcerative colitis azathioprine therapy clinical research. Results The effective rate of treatment in this group of patients was 88%, remission rate was 76%, erythrocyte sedimentation rate and C-reactive protein C decreased significantly, the difference was statistically significant (P<0.05), the incidence of adverse reaction was 30%. Conclusion Effect of treatment of refractory ulcerative colitis azathioprine good application, less adverse reaction, is worth the clinical promotion.