CAJ | 학술논문

目的：探讨双源CT 4维血管造影（4D- CTA）及灌注成像（CTPI）在急性脑缺血性疾病中的应用价值。方法对30例临床拟诊为急性脑缺血性疾病的患者于发病2~24h内行头颅CT平扫和全脑CTPI检查，获得脑血流量、脑血容量、平均通过时间、达峰时间等参数图，同时获得4D- CTA图像；于发病的1~3d后行MRI检查，分析CT平扫、CTPI、4D- CTA、MRI表现。结果 CT平扫发现12例有16个缺血病灶，CTPI发现26例32个缺血病灶，MRI发现25例28个缺血病灶，4D- CTA显示有20例责任血管有不同程度的狭窄或闭塞。结论双源CT 4D- CTA联合灌注成像能为急性脑缺血患者提供全面、详细的影像学信息，对急性缺血性脑梗死的早期诊断和治疗有重要价值。
목적：탐토쌍원CT 4유혈관조영（4D- CTA）급관주성상（CTPI）재급성뇌결혈성질병중적응용개치。방법대30례림상의진위급성뇌결혈성질병적환자우발병2~24h내행두로CT평소화전뇌CTPI검사，획득뇌혈류량、뇌혈용량、평균통과시간、체봉시간등삼수도，동시획득4D- CTA도상；우발병적1~3d후행MRI검사，분석CT평소、CTPI、4D- CTA、MRI표현。결과 CT평소발현12례유16개결혈병조，CTPI발현26례32개결혈병조，MRI발현25례28개결혈병조，4D- CTA현시유20례책임혈관유불동정도적협착혹폐새。결론쌍원CT 4D- CTA연합관주성상능위급성뇌결혈환자제공전면、상세적영상학신식，대급성결혈성뇌경사적조기진단화치료유중요개치。
Objective To investigate the application of dual- source four- dimensional CT angiography (4D- CTA) com-bined with CT perfusion imaging (CTPI) in diagnosis of acute cerebral ischemic diseases. Methods Thirty patients with clinical y suspected acute cerebral ischemic disease underwent head plain CT scan and whole brain CTPI examination 2~16h after onset, the images of CBF, CBV, MTT, TTP and 4D- CTA were obtained. Patients also underwent MRI examination in 1~3 d. The findings of plain CT scan, CTPI, 4D- CTA and MRI were analyzed. Results Plain CT scan found 16 ischemic lesions in 12 cases, CTPI found 32 ischemic lesions in 26 cases, MRI found 28 ischemic lesions in 25 cases, and 4D- CTA demonstrated various degree of stenosis or occlusion in supplying vessels in 20 cases. Conclusion Dual- source 4D- CTA combined with CT perfusion imaging provides comprehensive and detailed imaging information, so that has important value for early diagnosis and treatment in pa-tients with acute cerebral ischemia.