CAJ | 학술논문

目的：观察温肺止流丹治疗肺气虚，感受风寒型常年性变应性鼻炎的作用。方法选择常年性变应性鼻炎(肺气虚，感受风寒型)患者60例，随机分为温肺止流丹组和西替利嗪组。温肺止流丹组30例，口服温肺止流丹水煎剂2w，100ml/次，3次/d；西替利嗪组30例，口服西替利嗪，10mg/次/晚，服用2w。用药前、用药后1w及2w，记录患者的症状及体征评分及鼻分泌物涂片中的嗜酸性粒细胞计数。结果用药后1w时：温肺止流丹组显效17例，有效9例，无效4例；西替利嗪组显效18例，有效9例，无效3例，两组比较差异无统计学意义（P>0.05）；2w时：温肺止流丹组显效12例，有效7例，无效11例，西替利嗪组显效6例，有效7例，无效17例，温肺止流丹组优于西替利嗪组（P<0.01）；两组患者治疗后鼻腔分泌物涂片嗜酸性粒细胞计数显著减少。整个治疗期间未见明显不良反应报告。结论温肺止流丹治疗肺气虚，感受风寒型常年性变应性鼻炎疗效显著，未见明显副作用。
목적：관찰온폐지류단치료폐기허，감수풍한형상년성변응성비염적작용。방법선택상년성변응성비염(폐기허，감수풍한형)환자60례，수궤분위온폐지류단조화서체리진조。온폐지류단조30례，구복온폐지류단수전제2w，100ml/차，3차/d；서체리진조30례，구복서체리진，10mg/차/만，복용2w。용약전、용약후1w급2w，기록환자적증상급체정평분급비분비물도편중적기산성립세포계수。결과용약후1w시：온폐지류단조현효17례，유효9례，무효4례；서체리진조현효18례，유효9례，무효3례，량조비교차이무통계학의의（P>0.05）；2w시：온폐지류단조현효12례，유효7례，무효11례，서체리진조현효6례，유효7례，무효17례，온폐지류단조우우서체리진조（P<0.01）；량조환자치료후비강분비물도편기산성립세포계수현저감소。정개치료기간미견명현불량반응보고。결론온폐지류단치료폐기허，감수풍한형상년성변응성비염료효현저，미견명현부작용。
Objective To assess the ef icacy of Wenfeizhiliudan for perennial al ergic rhinitis. Methods Eighty patients with perennial al ergic rhinitis were randomly assigned to receive administration of 100ml of Wenfeizhiliudan (n=30), or 10mg of cetirizine tablet (n=30) by mouth for 14 days. Results At the one week point, improvement in the symptoms of the Wenfeizhiliudan group and the cetirizine group were similar (P>0.05). In the end of two weeks, the improvement in the symptoms of the Wenfeizhiliudan group was significant (P<0.01vs the cetirizine group). During the active drug administration Wenfeizhiliudan showed significantly decreases of eosinophilia (as assessed by nasal smear). No marked adverse ef ects were complained by patients. Conclusion The strategy for treating perennial al ergic rhinitis is the Wenfeizhiliudan, which provided clinical benefit in patients with perennial al ergic rhinitis.