CAJ | 학술논문

目的：探讨β-人绒毛膜促性腺激素（β-human chorionic gonadotropin ，β-HCG ）、孕酮（progesterone， P）对异位妊娠（ectopic pregnancy，EP）早期诊断的临床价值。方法回顾性分析2008～2012年柳州市第二妇幼保健院收治的50例EP患者（ A组）的临床资料，与同期50例宫内妊娠孕妇（ B组）相比较，观察两组间停经7周内与7周后的β-HCG、P水平的差异。通过ROC曲线分析确定EP的β-HCG、P临界值。结果停经7周内与7周后A组的β-HCG、P显著低于B组（ P＜0.05）。 ROC曲线分析显示，β-HCG、P的临界值分别为5321U/L、47 nmol/L时有较高的灵敏度和特异度。结论β-HCG与P对早期诊断EP有重要意义。
목적：탐토β-인융모막촉성선격소（β-human chorionic gonadotropin ，β-HCG ）、잉동（progesterone， P）대이위임신（ectopic pregnancy，EP）조기진단적림상개치。방법회고성분석2008～2012년류주시제이부유보건원수치적50례EP환자（ A조）적림상자료，여동기50례궁내임신잉부（ B조）상비교，관찰량조간정경7주내여7주후적β-HCG、P수평적차이。통과ROC곡선분석학정EP적β-HCG、P림계치。결과정경7주내여7주후A조적β-HCG、P현저저우B조（ P＜0.05）。 ROC곡선분석현시，β-HCG、P적림계치분별위5321U/L、47 nmol/L시유교고적령민도화특이도。결론β-HCG여P대조기진단EP유중요의의。
Objective To investigate the clinical value of beta human chorionic gonadotropin (β-HCG ) , progesterone ( P) in the early diagnosis of ectopic pregnancy .Methods A retrospective analysis of clinical data of 50 patients (group A) with the ectopic pregnancy during Jan .2008 to Dec.2012 in The second Maternal and Child Health Care Hospital of Liuzhou City were performed, compared with 50 cases of pregnancy (group B) over the same period.The β-HCG, progesterone levels of total cases in amenorrhea within 7 weeks and 7 weeks after were observed.And ROC curve was used in order to find the critical value of β-HCG, progesterone for diagnosis of ectopic pregnancy .Results Serum β-HCG of A group was significantly lower than B group ( P<0.05 ) .The ROC curve showed that critical value of β-HCG and progesterone were 5321U/L, 47nmol/L with higher sensitivity and specificity separately .Conclusion The serum β-HCG and progesterone have important significance in the early diagnosis of ectopic pregnancy .