CAJ | 학술논문

目的：探讨经皮射频消融术结合骨水泥成形术对疼痛性骨转移瘤的临床疗效。方法对8例经常规局部疗法及药物治疗未能缓解疼痛的骨转移患者进行了共计11次射频消融治疗。对椎弓、股骨、坐骨病变继消融术后追加骨水泥成形。术后随访8~12w，采用视觉模拟评分评价患者术前术后疼痛缓解程度，以配对t检验进行统计学分析。结果全体病例均顺利完成预定设计的治疗。术后1w内获得良好的镇痛疗效。术后2个月症状无复发。术后3d、1w、2wVSA值明显下降，有统计学意义（P<0.05）。结论经皮射频消融术对转移性骨肿瘤的疼痛及发展有良好的控制，可以明显提高患者的生存质量。
목적：탐토경피사빈소융술결합골수니성형술대동통성골전이류적림상료효。방법대8례경상규국부요법급약물치료미능완해동통적골전이환자진행료공계11차사빈소융치료。대추궁、고골、좌골병변계소융술후추가골수니성형。술후수방8~12w，채용시각모의평분평개환자술전술후동통완해정도，이배대t검험진행통계학분석。결과전체병례균순리완성예정설계적치료。술후1w내획득량호적진통료효。술후2개월증상무복발。술후3d、1w、2wVSA치명현하강，유통계학의의（P<0.05）。결론경피사빈소융술대전이성골종류적동통급발전유량호적공제，가이명현제고환자적생존질량。
Objective To discuss the clinical ef ectiveness of radiofrequency ablation (RFA)therapy in treat the painful bone metastases. Methods Eight patients with painful bone metastases who can't were control ed by conventional therapy were enrol ed in this study.Total 11 times of radiofrequency ablation treatment were undergone for the metastatic lesions. For the lesion of vertebral arch, thighbone, ischium PVP was performed fol ow the RFA. Al the patients were fol owed up for 8-12 weeks. The preoperative and postoperative pain severity was evaluated by visual analogue score (VSA). The results were statistical y analyzed by using T test with SPSS 11.0 statistical software. Result The procedure of RFA was successful y completed in al patients, and get satisfied results. Satisfied analgesic ef ect was achieved after 1 week. No recurrence of clinical symptoms was observed at 2 months after treatment. VAS at day 3, 1 week and 2 weeks was significantly decreased (P< 0.05). Conclusion Radiofrequency ablation therapy was proved especial y ef icacious in the relief of pain caused by bone metastases and improved the quality of life of the patients.