中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2013年
12期
1303-1304
,共2页
肾衰竭,慢性%前列地尔
腎衰竭,慢性%前列地爾
신쇠갈,만성%전렬지이
Kidney failure,chronic%Alprostadil
目的 观察前列地尔联合肾康注射液治疗老年人慢性肾衰竭的临床疗效. 方法 选择本院2010年2月至2013年2月间收治的老年慢性肾衰竭患者84例,随机分为治疗组和对照组.人选患者均给予常规治疗,治疗组给予前列地尔联合肾康注射液治疗;对照组给予肾康注射液治疗.结果 治疗组显效20例,有效12例,无效10例,总有效率为80.0％;对照组显效17例,有效12例,无效13例,总有效率为69.0％;两组治疗总有效率比较,差异无统计学意义(x2=0.539,p＝0.463).治疗后,治疗组血内生肌酐清除率高于对照组(t=1.931,P＝0.028);而血肌酐(t=1.999,P=0.024)、24 h尿蛋白(t=1.684,P=0.048)和血尿素氮(t=2.246,P=0.013)低于对照组. 结论 前列地尔联合肾康注射液治疗老年人慢性肾衰竭可有效改善肾功能相关指标.
目的 觀察前列地爾聯閤腎康註射液治療老年人慢性腎衰竭的臨床療效. 方法 選擇本院2010年2月至2013年2月間收治的老年慢性腎衰竭患者84例,隨機分為治療組和對照組.人選患者均給予常規治療,治療組給予前列地爾聯閤腎康註射液治療;對照組給予腎康註射液治療.結果 治療組顯效20例,有效12例,無效10例,總有效率為80.0％;對照組顯效17例,有效12例,無效13例,總有效率為69.0％;兩組治療總有效率比較,差異無統計學意義(x2=0.539,p＝0.463).治療後,治療組血內生肌酐清除率高于對照組(t=1.931,P＝0.028);而血肌酐(t=1.999,P=0.024)、24 h尿蛋白(t=1.684,P=0.048)和血尿素氮(t=2.246,P=0.013)低于對照組. 結論 前列地爾聯閤腎康註射液治療老年人慢性腎衰竭可有效改善腎功能相關指標.
목적 관찰전렬지이연합신강주사액치료노년인만성신쇠갈적림상료효. 방법 선택본원2010년2월지2013년2월간수치적노년만성신쇠갈환자84례,수궤분위치료조화대조조.인선환자균급여상규치료,치료조급여전렬지이연합신강주사액치료;대조조급여신강주사액치료.결과 치료조현효20례,유효12례,무효10례,총유효솔위80.0％;대조조현효17례,유효12례,무효13례,총유효솔위69.0％;량조치료총유효솔비교,차이무통계학의의(x2=0.539,p＝0.463).치료후,치료조혈내생기항청제솔고우대조조(t=1.931,P＝0.028);이혈기항(t=1.999,P=0.024)、24 h뇨단백(t=1.684,P=0.048)화혈뇨소담(t=2.246,P=0.013)저우대조조. 결론 전렬지이연합신강주사액치료노년인만성신쇠갈가유효개선신공능상관지표.
Objective To observe the clinical effect of alprostadil combined with Shenkang on chronic renal failure in elderly patients.Methods 84 elderly patients with chronic renal failure were chosen from Feb.2010 to Feb.2013,and divided into treatment group and control group.The patients were treated with alprostadil combined with Shenkang in treatment group,and were treated with Shenkang in control group.Clinical efficacy was compared between the two groups.Results In treatment group,clinical efficacy was markedly effective in 20 cases,effective in 12 cases and ineffective in 10 cases,and the total effective rate was 80.0％.In control group,clinical efficacy was markedly effective in 17 cases,effective in 12 cases and ineffective in 13 cases,and the total effective rate was 69.0％.There was no significant difference in total effective rate between groups (x2 =0.539,P＞0.05).There were no differences in the levels of serum creatinine clearance rate (Ccr) and creatinine (Scr),24 h urine protein (24-Upro) and blood urea nitrogen (BUN) between the two groups before treatment (all P＞0.05).After treatment,Ccr level was higher in treatment group than in control group (t=1.931,P＜0.05),and Scr,24-Upro and BUN levels were lower in treatment group than in control group (t=1.999,1.684,2.246,respectively,all P＜0.05).Conclusions Alprostadil combined with Shenkang can effectively improve the related renal function index in the treatment of elderly chronic renal failure,which is worthy of clinical application.
