北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2013年
9期
43-44
,共2页
胃排空%肠推进%CSP%阿托品
胃排空%腸推進%CSP%阿託品
위배공%장추진%CSP%아탁품
Gastric emptying%Intestinal propulsion%CSP%Atropine
目的:研究锁阳多糖(Cynomorium Songaircum polysalcharides,CSP)对小鼠胃肠运动的影响。方法:采用酚红标记的小鼠胃排空、小肠推进实验,观察CSP对正常小鼠胃排空、小肠推进影响以及对在阿托品负荷的小鼠胃排空、小肠推进抑制的影响。结果:CSP对小鼠的胃排空无显著影响(P>0.05),但对小肠的推进性蠕动作用明显(P<0.05),且成剂量依赖性。结论:CSP对小鼠胃排空的促进作用不明显,CSP对小鼠肠推进具有明显的促进作用,并且可以拮抗由阿托品引起的小鼠肠蠕动的抑制。
目的:研究鎖暘多糖(Cynomorium Songaircum polysalcharides,CSP)對小鼠胃腸運動的影響。方法:採用酚紅標記的小鼠胃排空、小腸推進實驗,觀察CSP對正常小鼠胃排空、小腸推進影響以及對在阿託品負荷的小鼠胃排空、小腸推進抑製的影響。結果:CSP對小鼠的胃排空無顯著影響(P>0.05),但對小腸的推進性蠕動作用明顯(P<0.05),且成劑量依賴性。結論:CSP對小鼠胃排空的促進作用不明顯,CSP對小鼠腸推進具有明顯的促進作用,併且可以拮抗由阿託品引起的小鼠腸蠕動的抑製。
목적:연구쇄양다당(Cynomorium Songaircum polysalcharides,CSP)대소서위장운동적영향。방법:채용분홍표기적소서위배공、소장추진실험,관찰CSP대정상소서위배공、소장추진영향이급대재아탁품부하적소서위배공、소장추진억제적영향。결과:CSP대소서적위배공무현저영향(P>0.05),단대소장적추진성연동작용명현(P<0.05),차성제량의뢰성。결론:CSP대소서위배공적촉진작용불명현,CSP대소서장추진구유명현적촉진작용,병차가이길항유아탁품인기적소서장연동적억제。
Objective:To study the effect of GSP on gastrointestinal motility in mice. Method:the gastric emptying, intestinal phenolsulfonphthalein propulsion experiments,the effects of CSP on gastric emptying,intestinal propulsion in normal mice and mice gastric emptying,intestinal propulsion in atropine loadinhibition effect. Results:there was no significant effect of CSP on mice gastric emptying (P>0.05),but on small intestinal propulsion significantly peristalsis function (P<0.05)in a dose-dependent;conclusion:CSP had less effect on gastric emptying in mice,CSP has obvious effect on small intestinal propulsion,suppression and can be antagonized by atropine due to the small intestinal peristalsis of mice.