CAJ | 학술논문

目的：观察茵栀黄注射液辅助治疗新生儿母乳性黄疸的临床疗效，探讨提高治疗新生儿母乳性黄疸疗效的措施。方法：选择2011年3月～2012年10月，在我院治疗的伴母乳性黄疸的新生儿96例，在患儿家长知情同意的情况下，均分为对照组（n=48例）和观察组（n=48例），对照组给予基础治疗，观察组给予基础治疗结合茵栀黄注射液辅助治疗，比较两组患儿治疗前后血清总胆红素（TBiL）水平的动态变化、治疗6d后的临床疗效及治疗过程中的不良反应情况。结果：两组患儿治疗1～6d中每天TBiL水平比较，差异均具有统计学意义（P＜0.05）；治疗6d后显效与好转例数比较，差异具有统计学意义（P＜0.05）；有效与无效例数比较，差异无统计学意义（P＞0.05）；两组患儿的不良反应例数比较，差异无统计学意义（P＞0.05），观察组优于对照组。结论：在新生儿母乳性黄疸的基础治疗中，应积极辅助茵栀黄注射液治疗，可促进患儿TBiL水平改善，提高临床疗效，且不增加治疗中的不良反应。
목적：관찰인치황주사액보조치료신생인모유성황달적림상료효，탐토제고치료신생인모유성황달료효적조시。방법：선택2011년3월～2012년10월，재아원치료적반모유성황달적신생인96례，재환인가장지정동의적정황하，균분위대조조（n=48례）화관찰조（n=48례），대조조급여기출치료，관찰조급여기출치료결합인치황주사액보조치료，비교량조환인치료전후혈청총담홍소（TBiL）수평적동태변화、치료6d후적림상료효급치료과정중적불량반응정황。결과：량조환인치료1～6d중매천TBiL수평비교，차이균구유통계학의의（P＜0.05）；치료6d후현효여호전례수비교，차이구유통계학의의（P＜0.05）；유효여무효례수비교，차이무통계학의의（P＞0.05）；량조환인적불량반응례수비교，차이무통계학의의（P＞0.05），관찰조우우대조조。결론：재신생인모유성황달적기출치료중，응적겁보조인치황주사액치료，가촉진환인TBiL수평개선，제고림상료효，차불증가치료중적불량반응。
Objective:To observe the clinical effect of Yinzhihuang injection adjuvant therapy for neonatal breast milk jaundice and research research the measures to improve the clinical effect.Method:Collect 96 neonates with neonatal breast milk jaundice,they were divided into the control group (n=48 patients)and the observation group (n=48 patients),compared with that the dynamic changes of serum bilirubin (TBiL)level before and after treatment,the clinical effect and adverse reactions after 6 days' treatment.Result:There was a significant(P<0.05)in the TBiL level during 6 days;there was a significant(P<0.05)in the number of markedly with improved cases;there was no significant (P>0.05)in the number of valid and invalid cases;there was no significant (P>0.05)in the number of adverse reactions cases,the observation group was better than the control group.Conclusion:During treating the neonatal breast milk jaundice,it should add the Yinzhihuang injection,ti could promote the improvement in children TBiL level,improve the clinical effect and did not increase the adverse reactions in the treatment.