CAJ | 학술논문

目的：研究黔产药用植物忽地笑中的化学成分。方法：采用多种色谱手段和重结晶等方法，分离纯化化合物；根据化合物的理化性质和波谱数据鉴定其结构。结果：从忽地笑鳞茎95%乙醇提取物的粗碱部位中分离得到7个单体化合物，均为生物碱，分别被鉴定为石蒜碱（lycorine，1），二氢石蒜碱（dihydrolycorine，2），加兰那敏（galanthamine，3），力可拉敏（lycoramine，4），那维定（narwedine，5），lycoraminone（6）和2-羟基-6-甲氧基香水仙灵（2-hydroxyl-6-O-methyloduline，7）。结论：化合物5、6和7均为首次从该植物中分离得到。
목적：연구검산약용식물홀지소중적화학성분。방법：채용다충색보수단화중결정등방법，분리순화화합물；근거화합물적이화성질화파보수거감정기결구。결과：종홀지소린경95%을순제취물적조감부위중분리득도7개단체화합물，균위생물감，분별피감정위석산감（lycorine，1），이경석산감（dihydrolycorine，2），가란나민（galanthamine，3），력가랍민（lycoramine，4），나유정（narwedine，5），lycoraminone（6）화2-간기-6-갑양기향수선령（2-hydroxyl-6-O-methyloduline，7）。결론：화합물5、6화7균위수차종해식물중분리득도。
Objective:To study the chemical constituents of Lycoris aurea from Guizhou province. Methods:All compounds were isolated and purified by by means of classic phytochemistry method and recrystallization. Their structures were identify by various spectral data and their physical characters. Results:Seven compounds (1-7)were isolated from the crude alkaloids extract of 95%ethanol of the material. Their structures were identified as lycorine(1),dihydrolycorine(2),galathanmine(3),lycoramine(4),narwedine(5), lycoraminone(6)and 2α-methoxy-6-O-ethyloduline(7). Conclusion:Compounds 5,6 and 7 were isolated from Lycoris aurea for the first time.