CAJ | 학술논문

线粒体与水通道4（AQP4）发挥正常生理功能是维持细胞代谢平衡、氧化还原平衡等的重要保障；当它们发生异常时，细胞就易遭受氧化应激和炎性损伤，最终导致多种慢性疾病的发生。探讨与它们功能异常有关的调控蛋白及信号通路对研究中药药理与治疗作用有重要的意义。
선립체여수통도4（AQP4）발휘정상생리공능시유지세포대사평형、양화환원평형등적중요보장；당타문발생이상시，세포취역조수양화응격화염성손상，최종도치다충만성질병적발생。탐토여타문공능이상유관적조공단백급신호통로대연구중약약리여치료작용유중요적의의。
Mitochondria and aquaporin 4 are of great physiological importance in cellular metabolism and redox homeostasis;with the malfunction of which, the cells/tissues would be readily injured by oxidative stress or inlfammation and culminate in some chronic diseases. Therefore, it is important to investigate the regulated proteins and signaling pathways of the malfunction of them in order to study the pharmacology and therapeutic effect of Chinese medicine.