中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
23期
48-49
,共2页
紫地宁血散%没食子酸%HPLC
紫地寧血散%沒食子痠%HPLC
자지저혈산%몰식자산%HPLC
Zidiningxuesan%Gallic acid%HPLC
目的建立测定紫地宁血散中没食子酸含量的方法。方法采用HPLC法，色谱柱为Diamond diamonsil C18柱，乙腈–含0.1%三乙胺的0.1%磷酸溶液（1∶99）为流动相，流速1.0mL/min，检测波长为273nm，柱温为30℃。结果没食子酸在20.475~2047.5ng范围内与其峰面积线性关系良好，平均回收率为100.5%，分析方法精密度（RSD）为0.4%（n=6）。结论所用方法简便、准确，能有效的控制该制剂的质量。
目的建立測定紫地寧血散中沒食子痠含量的方法。方法採用HPLC法，色譜柱為Diamond diamonsil C18柱，乙腈–含0.1%三乙胺的0.1%燐痠溶液（1∶99）為流動相，流速1.0mL/min，檢測波長為273nm，柱溫為30℃。結果沒食子痠在20.475~2047.5ng範圍內與其峰麵積線性關繫良好，平均迴收率為100.5%，分析方法精密度（RSD）為0.4%（n=6）。結論所用方法簡便、準確，能有效的控製該製劑的質量。
목적건립측정자지저혈산중몰식자산함량적방법。방법채용HPLC법，색보주위Diamond diamonsil C18주，을정–함0.1%삼을알적0.1%린산용액（1∶99）위류동상，류속1.0mL/min，검측파장위273nm，주온위30℃。결과몰식자산재20.475~2047.5ng범위내여기봉면적선성관계량호，평균회수솔위100.5%，분석방법정밀도（RSD）위0.4%（n=6）。결론소용방법간편、준학，능유효적공제해제제적질량。
Objective To establish an HPLC method for the determination of gallic acid in Zidiningxuesan. Methods A Diamond diamonsil C18 column was used, with the mobile phase of a mixture of acetonitrile and 0.1%solution of phosphoric acid containing 0.1%triethylamine (1∶99). The lfow rate was 1.0mL/min and the detective wavelength was 265nm. The column oven was 30℃. Results The standard curves were linear from 20.475 to 2047.5ng for gallic acid. The average recoveries was100.5%, RSD of the analysis method was 0.4%(n=6). Conclusion This method was simple, accurate and reliable for quality control of Zidiningxuesan.
