CAJ | 학술논문

目的分析慢性鼻窦炎鼻内镜术后应用辛夷冲洗液冲洗术腔的应用价值。方法采用随机数字表法将95例慢性鼻窦炎鼻内镜术后灌注液冲洗术腔患者分为两组，对照组予常规庆大霉素和地塞米松冲洗，观察组予庆大霉素、地塞米松联合辛夷冲洗液冲洗，首周2次/d，从第二周开始1次/d，连续治疗8周，观察两组患者鼻黏膜纤毛传输功能、T h细胞因子和嗜酸性粒细胞的变化。结果治疗8周末后，组间炎性鼻黏膜纤毛传输比较，P＜0.01；两组治疗后与治疗前Th1/Th2相关细胞因子水平比较，P＜0.01；组间IFN-r和IL-4水平比较，P＜0.1；组间IL-5水平比较，P＜0.5；组间IL-2水平比较，P＞0.05；组间嗜酸性粒细胞数目比较，P＜0.01。结论辛夷冲洗液能够直接作用于术腔，改善炎性鼻黏膜纤毛传输功能、Th1/Th2相关细胞因子水平和嗜酸性粒细胞数目，促进术腔黏膜修复和创面上皮化以提高慢性鼻窦炎鼻内镜术后的临床疗效，值得临床对中药鼻窦灌注液深入研究和推广。
목적분석만성비두염비내경술후응용신이충세액충세술강적응용개치。방법채용수궤수자표법장95례만성비두염비내경술후관주액충세술강환자분위량조，대조조여상규경대매소화지새미송충세，관찰조여경대매소、지새미송연합신이충세액충세，수주2차/d，종제이주개시1차/d，련속치료8주，관찰량조환자비점막섬모전수공능、T h세포인자화기산성립세포적변화。결과치료8주말후，조간염성비점막섬모전수비교，P＜0.01；량조치료후여치료전Th1/Th2상관세포인자수평비교，P＜0.01；조간IFN-r화IL-4수평비교，P＜0.1；조간IL-5수평비교，P＜0.5；조간IL-2수평비교，P＞0.05；조간기산성립세포수목비교，P＜0.01。결론신이충세액능구직접작용우술강，개선염성비점막섬모전수공능、Th1/Th2상관세포인자수평화기산성립세포수목，촉진술강점막수복화창면상피화이제고만성비두염비내경술후적림상료효，치득림상대중약비두관주액심입연구화추엄。
Objective To analyze chronic sinusitis after endoscopic sinus surgery applications Kobushi value of the surgical cavity washing fluid. Methods A random number table, rinse the surgical cavity patients were divided into two groups of 95 patients with chronic sinusitis, endoscopic sinus surgery perfusate, the control group treated with conventional and gentamycin dexamethasone rinse observation group to gentamicin, dexamethasone combined the Kobushi rinse liquid rinse first week 2 times/d, 1/d from the beginning of the second week, eight weeks of continuous treatment, mucociliary transport function were observed, the the Th cytokine and eosinophils changes. Results The treatment of 8 weeks, the group inflammatory nasal cilia transmission comparison, P<0.01; comparison with before treatment Th1/Th2 cytokine levels after treatment in the two groups, P<0.01; between groups IFN-r and IL-4 compared to P<0.1; IL-5 level comparison group, P<0.5; IL-2 levels between groups comparison, P> 0.05;eosinophils compared with the number in the group (P<0.01). Conclusion Magnolia rinse solution can directly act on the surgical cavity to improve inflammatory nasal cilia transmission function of Th1/Th2 the relevant cytokine levels and eosinophil number, to promote mucosal repair and wound epithelialization of the surgical cavity to improve chronic sinusitis the clinical efficacy of endoscopic sinus surgery, worthy of clinical in-depth research and promotion of Chinese medicine sinus perfusion fluid.