中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
10期
1470-1471
,共2页
他汀类药物%脑梗塞%高血压
他汀類藥物%腦梗塞%高血壓
타정류약물%뇌경새%고혈압
Statins%Brain infarction%Hypertension
目的 探讨他汀类药物对脑梗死患者的治疗效果以及对脑梗死复发的预防效果.方法 高血压动脉粥样性脑梗死患者108例,采用数字表法随机分为两组,每组54例.对照组采用常规治疗；观察组在常规治疗的基础上给予他汀类药物联合治疗.2个月后进行疗效评价,观察两组患者的血脂改善情况,比较两组的临床疗效,并统计两组患者在治疗后1年内脑梗死的复发情况.结果 观察组治疗后血脂等各项指标均优于对照组(均P＜0.05)；观察组总有效率100％,高于对照组的76％(x2=9.488,P＜0.05)；对照组复发12例(复发率22％),观察组复发1例(复发率2％),两组差异无统计学意义(x2=13.277,P＜0.05).结论 他汀类药物治疗和预防高血压动脉粥样性脑梗死有效、安全,值得在临床上推广使用.
目的 探討他汀類藥物對腦梗死患者的治療效果以及對腦梗死複髮的預防效果.方法 高血壓動脈粥樣性腦梗死患者108例,採用數字錶法隨機分為兩組,每組54例.對照組採用常規治療；觀察組在常規治療的基礎上給予他汀類藥物聯閤治療.2箇月後進行療效評價,觀察兩組患者的血脂改善情況,比較兩組的臨床療效,併統計兩組患者在治療後1年內腦梗死的複髮情況.結果 觀察組治療後血脂等各項指標均優于對照組(均P＜0.05)；觀察組總有效率100％,高于對照組的76％(x2=9.488,P＜0.05)；對照組複髮12例(複髮率22％),觀察組複髮1例(複髮率2％),兩組差異無統計學意義(x2=13.277,P＜0.05).結論 他汀類藥物治療和預防高血壓動脈粥樣性腦梗死有效、安全,值得在臨床上推廣使用.
목적 탐토타정류약물대뇌경사환자적치료효과이급대뇌경사복발적예방효과.방법 고혈압동맥죽양성뇌경사환자108례,채용수자표법수궤분위량조,매조54례.대조조채용상규치료；관찰조재상규치료적기출상급여타정류약물연합치료.2개월후진행료효평개,관찰량조환자적혈지개선정황,비교량조적림상료효,병통계량조환자재치료후1년내뇌경사적복발정황.결과 관찰조치료후혈지등각항지표균우우대조조(균P＜0.05)；관찰조총유효솔100％,고우대조조적76％(x2=9.488,P＜0.05)；대조조복발12례(복발솔22％),관찰조복발1례(복발솔2％),량조차이무통계학의의(x2=13.277,P＜0.05).결론 타정류약물치료화예방고혈압동맥죽양성뇌경사유효、안전,치득재림상상추엄사용.
Objective To explore the effect of statin in treatment of hypertensive atherosclerotic patients with cerebral infarction and the its effect in prevention cerebral infarction recurrence.Methods 108 hypertension patients with atherosclerotic cerebral infarction were randomly divided into two groups,each group had 54 cases.The control group received conventional treatment;the observation group was given combination therapy with statin and the conventional treatment.The efficacy was evaluated after 2 months.The blood pressure,blood lipid and cerebral function,cerebral infarction recurrence within 1 year after treatment in the two groups were observed.The clinical efficacy of the two groups was compared.Results After treatment,blood pressure,blood lipid indexes and brain function of the observation group were better than those of the control group(all P ＜ 0.05).The total effective rate of the observation group was 100％,which was higher than 76％ in the control group(x2 =9.488,P ＜ 0.05).The control group had 12 cases of recurrence(recurrence rate 22％),1 case recurrence in the observation group(recurrence rate 2％),with no significant difference between two groups (x2 =13.277,P ＜ 0.05).Conclusion The clinical efficacy of statins in the treatment and prevention of hypertension atherosclerotic cerebral infarction is safe and significant,which is worth to use in clinical practice.
