CAJ | 학술논문

目的：探讨不同频率振法对制动肌肉萎缩大鼠神经纤维的trpv1的通道表达的影响。方法：采用SD大鼠72只，随机分为空白组和模型组，A组（100次/min，5min）、B组（300次/min，5min）、C组（500次/min，5min）、D组（800次/min，5min），每组12只；模型组大鼠以后肢制动方法为废用模型，制动一周后，A、B、C、D组予振法干预，每日2次。干预1周后，比较各组大鼠比目鱼肌神经纤维的trpv1的通道表达。结果：模型组的比目鱼肌神经纤维的trpv1表达弱于空白组，300次/min、500次/min组的trpv1表达强于空白组，有显著差异，300次/min最佳。结论：制动大鼠肌肉萎缩的神经冲动呈减弱趋势，振法可以促进制动大鼠肌肉萎缩的神经冲动，以300次/分最佳。
목적：탐토불동빈솔진법대제동기육위축대서신경섬유적trpv1적통도표체적영향。방법：채용SD대서72지，수궤분위공백조화모형조，A조（100차/min，5min）、B조（300차/min，5min）、C조（500차/min，5min）、D조（800차/min，5min），매조12지；모형조대서이후지제동방법위폐용모형，제동일주후，A、B、C、D조여진법간예，매일2차。간예1주후，비교각조대서비목어기신경섬유적trpv1적통도표체。결과：모형조적비목어기신경섬유적trpv1표체약우공백조，300차/min、500차/min조적trpv1표체강우공백조，유현저차이，300차/min최가。결론：제동대서기육위축적신경충동정감약추세，진법가이촉진제동대서기육위축적신경충동，이300차/분최가。
Objective:To investigate effects of expression of different frequency ofbrake muscle atrophy of nerve fiber in the rat TRPV1 channels. Methods:72 SD rats,were randomly divided into blank group and model group. Group A (100,/min, 5min),B group (300/min, 5min), C group (500/min, 5min), D group (800/min, 5min), 12 rats in each group, male and female half of the rats in the model group;after the limbbraking method for disuse model, brake after a week, A, B, C, D group were treated with vibration method intervention, 2 times a day. 1 weeks after the interventiongroups were compared, the expression of rat soleus muscle nerve fibers of theTRPV1 channel. Results:the soleus nerve fiber model group TRPV1 was lower thanthe blank group, 300/min, 500/min group of TRPV1 is stronger than that in the blank group, there are significant differences, the 300/min is best. Conclusion:the nerve impulse brake rat muscle atrophy of the weakening trend, vibration method can promote the nerve impulse brake rat muscle atrophy in 300/min is the best.