中国保健营养(中旬刊)
中國保健營養(中旬刊)
중국보건영양(중순간)
China Hwalth Care & nutrition
2013年
3期
12-13
,共2页
病毒性脑炎%心肌炎%基质金属蛋白酶-9%心肌钙蛋白Ⅰ
病毒性腦炎%心肌炎%基質金屬蛋白酶-9%心肌鈣蛋白Ⅰ
병독성뇌염%심기염%기질금속단백매-9%심기개단백Ⅰ
Viral encephalitis%Myocarditis%Matrix metalloproteinase-9%Myocardial calcium proteinⅠ
目的:探讨基质金属蛋白酶-9(MMP-9)联合心肌钙蛋白Ⅰ(CTnI)检测对病毒性脑炎合并心肌炎早期诊断的意义。方法:选择90例符合病毒性脑炎诊断患儿,按有无合并心肌炎情况分为两组,其中病毒性脑炎组50例,合并心肌炎组40例,并选取20例健康体检儿童为对照组。所有受试者均测定血清MMP-9和CTnI水平。结果:病毒性脑炎合并心肌炎和病毒性脑炎组患儿与对照组MMP-9首次测定分别为423.18±99.26、293.23±75.9、118.89±66.87;三组CTnI首次测定为2.73±1.25、0.76±0.53。与对照组相比,病毒性脑炎组和病毒性脑炎合并心肌炎患儿MMP-9、CTnI水平明显升高,p均<0.05,且合并心肌炎者血清MMP-9、CTnI水平亦显著高于病毒性脑炎组(p<0.05)。结论:血清MMP-9联合CTnI检测在病毒性心肌炎的早期诊断中有重要意义。
目的:探討基質金屬蛋白酶-9(MMP-9)聯閤心肌鈣蛋白Ⅰ(CTnI)檢測對病毒性腦炎閤併心肌炎早期診斷的意義。方法:選擇90例符閤病毒性腦炎診斷患兒,按有無閤併心肌炎情況分為兩組,其中病毒性腦炎組50例,閤併心肌炎組40例,併選取20例健康體檢兒童為對照組。所有受試者均測定血清MMP-9和CTnI水平。結果:病毒性腦炎閤併心肌炎和病毒性腦炎組患兒與對照組MMP-9首次測定分彆為423.18±99.26、293.23±75.9、118.89±66.87;三組CTnI首次測定為2.73±1.25、0.76±0.53。與對照組相比,病毒性腦炎組和病毒性腦炎閤併心肌炎患兒MMP-9、CTnI水平明顯升高,p均<0.05,且閤併心肌炎者血清MMP-9、CTnI水平亦顯著高于病毒性腦炎組(p<0.05)。結論:血清MMP-9聯閤CTnI檢測在病毒性心肌炎的早期診斷中有重要意義。
목적:탐토기질금속단백매-9(MMP-9)연합심기개단백Ⅰ(CTnI)검측대병독성뇌염합병심기염조기진단적의의。방법:선택90례부합병독성뇌염진단환인,안유무합병심기염정황분위량조,기중병독성뇌염조50례,합병심기염조40례,병선취20례건강체검인동위대조조。소유수시자균측정혈청MMP-9화CTnI수평。결과:병독성뇌염합병심기염화병독성뇌염조환인여대조조MMP-9수차측정분별위423.18±99.26、293.23±75.9、118.89±66.87;삼조CTnI수차측정위2.73±1.25、0.76±0.53。여대조조상비,병독성뇌염조화병독성뇌염합병심기염환인MMP-9、CTnI수평명현승고,p균<0.05,차합병심기염자혈청MMP-9、CTnI수평역현저고우병독성뇌염조(p<0.05)。결론:혈청MMP-9연합CTnI검측재병독성심기염적조기진단중유중요의의。
Objective:To matrix metalloproteinase-9 (MMP- 9) combined with myocardial calcium proteinⅠ (CTnI) detection of viral encephalitis combined myocarditis early diagnosis significance. Methods:Atotal of 90 patients with diagnosis of children with viral encephalitis, according to whether merger myocarditis situation divided into two groups, including viral encephalitis group of fifty cases, combined with myocarditis group and an example, and select twenty cases of healthy check-up children as control group. All respondents were measured serum levels of MMP-9 and CTnI levels. Results:The viral encephalitis combined myocarditis and viral encephalitis group and control group with MMP-9 first measurement were 423.18+/-99.26, 293.23+/-75.9, 118.89 66.87 mm;Three groups of CTnI determination for the first time was 2.73+/-1.25, 0.76+/-0.53. Compared with the control, viral encephalitis group and viral encephalitis combined with myocarditis MMP-9, CTnI levels increased significantly, p<0.05, and the merger myocarditis serum MMP-9, CTnI levels also significantly higher than that of viral encephalitis group (p<0.05). Conclusion:Serum MMP-9 joint CTnI detection in the early diagnosis of viral myocarditis is of important significance.