中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
11期
42-43
,共2页
奎硫平%利培酮%阿尔茨海默病%精神行为症状
奎硫平%利培酮%阿爾茨海默病%精神行為癥狀
규류평%리배동%아이자해묵병%정신행위증상
Quetiapine%Risperidone%Alzheimer's disease%The behavioral and psychological symptoms
目的：比较奎硫平和利培酮对阿尔茨海默病(AD)患者精神行为症状(BPSD)的疗效和安全性。方法：收治具有精神行为症状的AD患者60例，随机分为两组，分别给予奎硫平和利培酮治疗，疗程6周。采用痴呆病理行为评定量表(BEHAVE-AD)、简易智力状态检查(MMSE)评定疗效。采用副反应量表(TESS)评定不良反应。结果：奎硫平组的有效率84.5%；利培酮组的有效率83%。结论：奎硫平的安全性更高。
目的：比較奎硫平和利培酮對阿爾茨海默病(AD)患者精神行為癥狀(BPSD)的療效和安全性。方法：收治具有精神行為癥狀的AD患者60例，隨機分為兩組，分彆給予奎硫平和利培酮治療，療程6週。採用癡呆病理行為評定量錶(BEHAVE-AD)、簡易智力狀態檢查(MMSE)評定療效。採用副反應量錶(TESS)評定不良反應。結果：奎硫平組的有效率84.5%；利培酮組的有效率83%。結論：奎硫平的安全性更高。
목적：비교규류평화리배동대아이자해묵병(AD)환자정신행위증상(BPSD)적료효화안전성。방법：수치구유정신행위증상적AD환자60례，수궤분위량조，분별급여규류평화리배동치료，료정6주。채용치태병리행위평정량표(BEHAVE-AD)、간역지력상태검사(MMSE)평정료효。채용부반응량표(TESS)평정불량반응。결과：규류평조적유효솔84.5%；리배동조적유효솔83%。결론：규류평적안전성경고。
Objective:To compare the efficacy and safety of quetiapine and risperidone in the treatment of alzheimer's disease(AD) patients with behavioral and psychological symptoms(BPSD).Methods:60 cases of AD patients with behavioral and psychological symptoms were selected,they were randomly divided into two groups.The two groups were respectively treated with quetiapine and risperidone for 6 weeks.Treatment effects were assessed with the behavioral pathology in alzheimer's disease rating scale(BEHAVE-AD) and mini mental state examination(MMSE).Adverse reactions were assessed with treatment emergent symptom scale(TESS).Results:In the quetiapine group,the effective rate was 84.5%;in the risperidone group,the effective rate was 83%.Conclusion:The safety of quetiapine is higher.
